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voltage-dependent anion channel 1

Summary

Gene Symbol

Vdac1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22333

KEGG Gene ID

PubChem

22333

Alliance of Genome Resources

MGI:106919

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
Apoptosis
Cell membrane
Direct protein sequencing
Isopeptide bond
Lipid transport
Lipid-binding
Mitochondrion outer membrane
NAD
Phosphoprotein
Porin
Reference proteome
Transmembrane beta strand
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q60932	Outer mitochondrial membrane protein porin 1 Plasmalemmal porin Voltage-dependent anion-selective channel protein 1 Voltage-dependent anion-selective channel protein 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 32 in total

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GO Term	Evidence Code	PMID
behavioral fear response	IMP
pyruvate decarboxylation to acetyl-CoA	ISO
anion transport	ISO
monoatomic anion transport	ISO
anion transport	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

neuron-neuron synaptic transmission

metabolic process [inference]

sulfur compound metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

sulfur compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

sulfur compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

purine-containing compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

purine-containing compound metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

purine-containing compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

cell death [inference]

programmed cell death [inference]

apoptotic process

intercellular transport [inference]

calcium import into the mitochondrion

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation

cellular localization [inference]

intracellular transport [inference]

mitochondrial transport [inference]

mitochondrial transmembrane transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

monoatomic anion transmembrane transport

mitochondrial transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning

behavior [inference]

behavioral defense response [inference]

behavioral fear response

learning or memory [inference]

learning

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

monoatomic anion transport

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

monoatomic anion transmembrane transport

lipid transport

intercellular transport [inference]

calcium import into the mitochondrion

intracellular transport [inference]

mitochondrial transport [inference]

mitochondrial transmembrane transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

monoatomic anion transmembrane transport

mitochondrial transmembrane transport

establishment of localization in cell [inference]

intracellular transport [inference]

mitochondrial transport [inference]

mitochondrial transmembrane transport

cellular localization [inference]

intracellular transport [inference]

mitochondrial transport [inference]

mitochondrial transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

neuron-neuron synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium import into the mitochondrion [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of calcium ion transmembrane transport [inference]

regulation of calcium import into the mitochondrion [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium import into the mitochondrion [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of reactive oxygen species metabolic process

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of cellular process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of reactive oxygen species metabolic process

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

regulation of autophagy [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

regulation of macroautophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

regulation of mitophagy

positive regulation of mitophagy

positive regulation of type 2 mitophagy

regulation of type 2 mitophagy [inference]

positive regulation of type 2 mitophagy

regulation of autophagy of mitochondrion [inference]

regulation of mitophagy

positive regulation of mitophagy

positive regulation of type 2 mitophagy

regulation of type 2 mitophagy [inference]

positive regulation of type 2 mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

regulation of reactive oxygen species metabolic process [inference]

negative regulation of reactive oxygen species metabolic process

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium import into the mitochondrion [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

positive regulation of type 2 mitophagy

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of reactive oxygen species metabolic process

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium import into the mitochondrion

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

Displaying entries **1 - 5** of 33 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	IDA
mitochondrion	IEA
mitochondrion	HDA
mitochondrial outer membrane	ISS

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

pore complex [inference]

mitochondrial permeability transition pore complex

mitochondrial protein-containing complex [inference]

mitochondrial permeability transition pore complex

cellular anatomical structure [inference]

nucleoid [inference]

mitochondrial nucleoid

membrane

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic active zone membrane

postsynaptic specialization membrane [inference]

postsynaptic density membrane

membrane microdomain [inference]

membrane raft

myelin sheath

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

membraneless organelle [inference]

intracellular membraneless organelle [inference]

mitochondrial nucleoid

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membraneless organelle [inference]

mitochondrial nucleoid

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GO Term	Evidence Code	PMID
voltage-gated monoatomic ion channel activity	ISS
voltage-gated monoatomic ion channel activity	ISO
voltage-gated monoatomic ion channel activity	IEA
monoatomic anion channel activity	ISO
protein binding	IPI