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Guidelines

MIRAGE

eukaryotic translation initiation factor 4 gamma, 3

Summary

Gene Symbol

Eif4g3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

230861

KEGG Gene ID

PubChem

230861

Alliance of Genome Resources

MGI:1923935

Annotation

Keyword

Alternative splicing
Coiled coil
Initiation factor
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Repeat
Translation regulation

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A0R4J112
A2AMI2
Q8BQR8
Q80XI3	eIF-4-gamma II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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2

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GO Term	Evidence Code	PMID
positive regulation of protein phosphorylation	IMP
translational initiation	NAS
translational initiation	IBA
regulation of translation
spermatogenesis	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

translational initiation

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

spermatid development

cellular developmental process [inference]

cell development [inference]

germ cell development [inference]

spermatid development

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

spermatid development

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

spermatid development

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

spermatid development

spermatogenesis

anatomical structure development [inference]

cell development [inference]

germ cell development [inference]

spermatid development

cellular developmental process [inference]

cell development [inference]

germ cell development [inference]

spermatid development

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of translation

positive regulation of cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

positive regulation of translation

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of translation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

positive regulation of translation

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of translation

regulation of protein metabolic process [inference]

regulation of translation

positive regulation of translation

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of translation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation

positive regulation of translation

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of translation

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of translation

positive regulation of cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of nuclear division [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of meiosis I [inference]

positive regulation of meiosis I

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of meiosis I [inference]

positive regulation of meiosis I

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of meiosis I [inference]

positive regulation of meiosis I

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of meiosis I [inference]

positive regulation of meiosis I

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	IDA
cytoplasm	IEA
eukaryotic translation initiation factor 4F complex	NAS
eukaryotic translation initiation factor 4F complex	IBA
synapse	EXP

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

RNA cap binding complex [inference]

eukaryotic translation initiation factor 4F complex

cellular anatomical structure [inference]

cytoplasm

cell junction [inference]

synapse

Displaying **all 5** entries
GO Term	Evidence Code	PMID
RNA binding	IEA
mRNA binding	IBA
translation initiation factor activity	IDA
translation initiation factor activity	IBA
protein binding	IPI

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

mRNA binding

protein binding

translation factor activity [inference]

translation initiation factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Eukaryotic translation initiation factor 4 gamma

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
InterPro
Armadillo-type fold
Initiation factor 4G
Initiation factor eIF-4 gamma, MA3
MIF4G-like, type 3
W2 domain

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	43839	FB:FBgn0023213
Homo sapiens	8672	HGNC:3298
Saccharomyces cerevisiae S288C	852833	SGD:S000003017
Saccharomyces cerevisiae S288C	853071	SGD:S000003394

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026