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non-SMC condensin II complex subunit D3

Summary

Gene Symbol

NCAPD3

Organism

Homo sapiens (human)

External Links

NCBI Gene

23310

PubChem

23310

Alliance of Genome Resources

HGNC:28952

Annotation

Keyword

Coiled coil
DNA condensation
Disease variant
Mitosis
Nucleus
Phosphoprotein
Primary microcephaly
Reference proteome
Repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
P42695	Non-SMC condensin II complex subunit D3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
mitotic chromosome condensation	IDA	14532007
mitotic chromosome condensation	IMP	27737959
mitotic chromosome condensation	IBA
meiotic chromosome condensation	IBA
cell division	IEA

GO Hierarchy

biological process

cellular process [inference]

cell cycle process [inference]

meiotic cell cycle process [inference]

chromosome organization involved in meiotic cell cycle [inference]

meiotic chromosome condensation

mitotic cell cycle process [inference]

mitotic chromosome condensation

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

chromosome condensation [inference]

chromosome organization involved in meiotic cell cycle [inference]

meiotic chromosome condensation

reproductive process [inference]

meiotic cell cycle process [inference]

chromosome organization involved in meiotic cell cycle [inference]

meiotic chromosome condensation

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

regulation of chromosome organization [inference]

regulation of chromosome condensation [inference]

positive regulation of chromosome condensation

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of chromosome segregation [inference]

positive regulation of chromosome segregation

regulation of chromosome separation [inference]

positive regulation of chromosome separation

positive regulation of cell cycle process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
condensed chromosome, centromeric region	IBA
condensed nuclear chromosome	ISO
condensin complex	NAS	17268547
condensin complex	IDA	14532007
condensin complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

condensin complex

protein-DNA complex [inference]

chromatin [inference]

heterochromatin [inference]

pericentric heterochromatin

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

nuclear chromosome [inference]

condensed nuclear chromosome

condensed chromosome [inference]

condensed nuclear chromosome

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

nuclear chromosome [inference]

condensed nuclear chromosome

condensed chromosome [inference]

condensed nuclear chromosome

chromosomal region [inference]

chromosome, centromeric region [inference]

condensed chromosome, centromeric region

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	17268547 23728299 26496610 29028794 33961781
methylated histone binding	IDA	20622854
histone binding	IBA

GO Hierarchy

methylated histone binding

modification-dependent protein binding [inference]

methylation-dependent protein binding [inference]

methylated histone binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

condensin-2 complex subunit

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
histone binding
meiotic chromosome condensation
mitotic chromosome condensation

Displaying **all 4** entries
InterPro
Armadillo-like helical
Armadillo-type fold
Condensin complex subunit 1, C-terminal
Condensin subunit 1/Condensin-2 complex subunit D3

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070296	primary autosomal recessive microcephaly	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Orthologous MAtrix
Melopsittacus undulatus	101871045	MELUD17539
Chrysemys picta bellii	101930975	CHRPI14741
Chinchilla lanigera	102029491	CHILA03646
Macaca fascicularis	102132696	MACFA10800
Capra hircus	102178558	CAPHI05121
Myotis lucifugus	102437310	MYOLU11071
Pelodiscus sinensis	102450522	PELSI08519
Erinaceus europaeus	103121223	ERIEU12667
Ornithorhynchus anatinus	103167432	ORNAN03546
Callorhinchus milii	103180303	CALMI20089

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Acknowledgements