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MIRAGE
SLIT-ROBO Rho GTPase activating protein 2
Summary
- Gene Symbol
-
- SRGAP2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cell projection
- Chromosomal rearrangement
- Coiled coil
- Cytoplasm
- Cytoplasmic vesicle
- GTPase activation
- Methylation
- Neurogenesis
- Nucleus
- Phosphoprotein
- Postsynaptic cell membrane
- Proteomics identification
- Reference proteome
- SH3 domain
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A075B7B5 |
|
| O75044 |
|
| B7Z3G4 |
|
| B7ZM87 |
|
| B4DFE5 |
|
| A0A1S5UZH8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lamellipodium assembly involved in ameboidal cell migration |
|
|
| signal transduction |
|
|
| nervous system development |
|
|
| extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration |
|
|
| negative regulation of cell migration |
|
GO Hierarchy
biological process
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| GTPase activator activity |
|
|
| GTPase activator activity |
|
|
| GTPase activator activity |
|
|
| GTPase activator activity |
|
|
| GTPase activator activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- slit-robo rho gtpase-activating
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| negative regulation of cell migration |
| InterPro |
|---|
| AH/BAR domain superfamily |
| F-BAR domain |
| FCH domain |
| Rho GTPase activation protein |
| Rho GTPase-activating protein domain |
| SH3 domain |
| SH3-like domain superfamily |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 14270 | MGI:109605 |
