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arginine vasopressin

Summary

Gene Symbol

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24221

KEGG Gene ID

[""]

PubChem

24221

Alliance of Genome Resources

RGD:2184

Annotation

Keyword

Amidation
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Glycoprotein
Hormone
Reference proteome
Secreted
Signal
Vasoconstrictor

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P01186	AVP-NPII
A6HQA1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 49 in total

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GO Term	Evidence Code	PMID
temperature homeostasis	TAS
maternal aggressive behavior	IMP
maternal aggressive behavior	IBA
maternal aggressive behavior	IEA
positive regulation of systemic arterial blood pressure	IDA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

intracellular signal transduction

reproductive process [inference]

multicellular organismal reproductive process [inference]

reproductive behavior [inference]

mating behavior [inference]

female mating behavior [inference]

regulation of female receptivity

negative regulation of female receptivity

parental behavior [inference]

maternal behavior

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

vasoconstriction

renal system process [inference]

renal water transport [inference]

renal water absorption

renal absorption [inference]

renal water absorption

behavior [inference]

aggressive behavior [inference]

maternal aggressive behavior

reproductive behavior [inference]

mating behavior [inference]

female mating behavior [inference]

regulation of female receptivity

negative regulation of female receptivity

parental behavior [inference]

maternal behavior

social behavior

multicellular organismal response to stress

multicellular organismal-level homeostasis [inference]

temperature homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

multicellular organismal-level homeostasis [inference]

temperature homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

intracellular monoatomic cation homeostasis [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

symbiont entry into host [inference]

symbiont entry into host cell

response to stimulus [inference]

response to stress [inference]

response to osmotic stress [inference]

response to salt stress

multicellular organismal response to stress

response to abiotic stimulus [inference]

response to osmotic stress [inference]

response to salt stress

response to electrical stimulus

response to endogenous stimulus [inference]

response to growth factor [inference]

response to nerve growth factor

response to chemical [inference]

response to xenobiotic stimulus

response to lipid [inference]

response to testosterone

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol

response to ketone [inference]

response to testosterone

response to 2,3,7,8-tetrachlorodibenzodioxine

localization [inference]

establishment of localization [inference]

transport [inference]

fluid transport [inference]

water transport [inference]

renal water transport [inference]

renal water absorption

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of organic acid transport [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of organic acid transport [inference]

positive regulation of glutamate secretion

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of glutamate secretion

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of amine transport [inference]

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of amino acid transport [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of cell growth

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of glutamate secretion

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

intracellular signal transduction

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse

regulation of transmission of nerve impulse [inference]

negative regulation of transmission of nerve impulse

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of small molecule metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of cell growth

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse

regulation of transmission of nerve impulse [inference]

negative regulation of transmission of nerve impulse

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

regulation of blood pressure [inference]

positive regulation of blood pressure [inference]

positive regulation of systemic arterial blood pressure

regulation of female receptivity

negative regulation of female receptivity

regulation of body fluid levels [inference]

multicellular organismal-level water homeostasis

regulation of intracellular pH [inference]

intracellular pH reduction

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

vasoconstriction

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	IDA
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

dense core granule [inference]

neuronal dense core vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

dense core granule [inference]

neuronal dense core vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

dense core granule [inference]

neuronal dense core vesicle

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
protein kinase activity	ISO
protein kinase activity	IEA
hormone activity	ISO
neuropeptide hormone activity	ISO
neuropeptide hormone activity	IDA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

vasopressin receptor binding [inference]

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

neuropeptide hormone activity

neurohypophyseal hormone activity

neuropeptide activity [inference]

neuropeptide hormone activity

neurohypophyseal hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

neuropeptide hormone activity

neurohypophyseal hormone activity

neuropeptide activity [inference]

neuropeptide hormone activity

neurohypophyseal hormone activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

neurophysin 1

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
hormone activity
neurohypophyseal hormone activity
neuropeptide hormone activity

Displaying **all 3** entries
InterPro
Neurohypophysial hormone domain superfamily
Neurohypophysial hormone, conserved site
Neurohypophysial hormone

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
dendrite	PMID:12829321 PMID:18483147
extracellular space	PMID:18596120
secretory granule	PMID:18483147

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:10762	portal hypertension	Alliance of Genome Resources
DOID:3328	temporal lobe epilepsy	Alliance of Genome Resources
DOID:4195	hyperglycemia	Alliance of Genome Resources
DOID:9409	diabetes insipidus	Alliance of Genome Resources
DOID:9744	type 1 diabetes mellitus	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements