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Vasopressin-neurophysin 2-copeptin

Summary

UniProt ID

P01186

Gene Symbol

Gene ID

24221

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P01186
PubChem: P01186
Re-Glyco: P01186

Annotation

Keyword

Amidation
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Glycoprotein
Hormone
Reference proteome
Secreted
Signal
Vasoconstrictor

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
secretory granule
dendrite
extracellular region
extracellular space
neuronal dense core vesicle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 26 in total

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GO Term
negative regulation of transmission of nerve impulse
temperature homeostasis
locomotory behavior
positive regulation of cell population proliferation
positive regulation of gene expression
positive regulation of glutamate secretion
positive regulation of cell growth
social behavior
intracellular signal transduction
negative regulation of apoptotic process

Displaying **all 7** entries
GO Term
neurohypophyseal hormone activity
V1A vasopressin receptor binding
V1B vasopressin receptor binding
V2 vasopressin receptor binding
protein kinase activity
neuropeptide hormone activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Annotation information from UniProt.

Sequence

MLAMMLNTTLSACFLSLLALTSACYFQNCPRGGKRATSDMELRQCLPCGPGGKGRCFGPSICCADELGCFLGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCSDESCVAEPECREGFFRLTRAREQSNATQLDGPARELLLRLVQLAGTQESVDSAKPRVY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
135			G88725PI	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Rattus norvegicus
Clathrin-mediated endocytosis	Rattus norvegicus
G alpha (q) signalling events	Rattus norvegicus
Transport of organic anions	Rattus norvegicus
Vasopressin regulates renal water homeostasis via Aquaporins	Rattus norvegicus
Vasopressin-like receptors	Rattus norvegicus

Disease

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:10762	portal hypertension	Alliance of Genome Resources
DOID:3328	temporal lobe epilepsy	Alliance of Genome Resources
DOID:4195	hyperglycemia	Alliance of Genome Resources
DOID:9409	diabetes insipidus	Alliance of Genome Resources
DOID:9744	type 1 diabetes mellitus	Alliance of Genome Resources