GlyCosmos Portal

Submissions

Vasopressin-neurophysin 2-copeptin

Summary

UniProt ID

P01186

Gene Symbol

Gene ID

24221

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P01186
PubChem: P01186
Re-Glyco: P01186

Annotation

Keyword: Amidation Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Hormone Reference proteome Secreted Signal Vasoconstrictor

Gene Ontology (GO)

Displaying entries **1 - 5** of 47 in total

1

2

3

4

5

…

Next ›

Last »
GO Term	Evidence Code	Reference
temperature homeostasis	TAS	PMID
maternal aggressive behavior	IMP	PMID
maternal aggressive behavior	IBA	GO_REF
maternal aggressive behavior	IEA	GO_REF
positive regulation of systemic arterial blood pressure	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

intracellular signal transduction

reproductive process [inference]

multicellular organismal reproductive process [inference]

reproductive behavior [inference]

mating behavior [inference]

female mating behavior [inference]

regulation of female receptivity [inference]

negative regulation of female receptivity

parental behavior [inference]

maternal behavior

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

vasoconstriction

renal system process [inference]

renal water transport [inference]

renal water absorption

renal absorption [inference]

renal water absorption

behavior [inference]

aggressive behavior [inference]

maternal aggressive behavior

reproductive behavior [inference]

mating behavior [inference]

female mating behavior [inference]

regulation of female receptivity [inference]

negative regulation of female receptivity

parental behavior [inference]

maternal behavior

social behavior

multicellular organismal response to stress

multicellular organismal-level homeostasis [inference]

temperature homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

symbiont entry into host [inference]

symbiont entry into host cell

response to stimulus [inference]

response to stress [inference]

response to osmotic stress [inference]

response to salt stress

multicellular organismal response to stress

response to abiotic stimulus [inference]

response to osmotic stress [inference]

response to salt stress

response to electrical stimulus

response to endogenous stimulus [inference]

response to growth factor [inference]

response to nerve growth factor

response to chemical [inference]

response to xenobiotic stimulus

response to lipid [inference]

response to testosterone

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol

response to ketone [inference]

response to testosterone

response to 2,3,7,8-tetrachlorodibenzodioxine

localization [inference]

establishment of localization [inference]

transport [inference]

fluid transport [inference]

water transport [inference]

renal water transport [inference]

renal water absorption

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of organic acid transport [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of organic acid transport [inference]

positive regulation of glutamate secretion

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of glutamate secretion

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of amine transport [inference]

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of amino acid transport [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of cell growth

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of glutamate secretion

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

intracellular signal transduction

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse

regulation of transmission of nerve impulse [inference]

negative regulation of transmission of nerve impulse

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of small molecule metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of unsaturated fatty acid biosynthetic process [inference]

regulation of prostaglandin biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process [inference]

positive regulation of unsaturated fatty acid biosynthetic process [inference]

positive regulation of prostaglandin biosynthetic process

positive regulation of cell growth

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of secretion by cell [inference]

positive regulation of glutamate secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse

regulation of transmission of nerve impulse [inference]

negative regulation of transmission of nerve impulse

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

regulation of blood pressure [inference]

positive regulation of blood pressure [inference]

positive regulation of systemic arterial blood pressure

regulation of female receptivity [inference]

negative regulation of female receptivity

regulation of body fluid levels [inference]

multicellular organismal-level water homeostasis

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

vasoconstriction

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
extracellular region	ISO	GO_REF
extracellular region	IDA	PMID PMID PMID
extracellular region	IEA	GO_REF GO_REF GO_REF
obsolete extracellular space
secretory granule	IDA	PMID PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

dense core granule [inference]

neuronal dense core vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

dense core granule [inference]

neuronal dense core vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

dense core granule [inference]

neuronal dense core vesicle

Displaying entries **1 - 5** of 15 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	Reference
protein kinase activity	ISO	GO_REF
protein kinase activity	IEA	GO_REF
hormone activity	ISO	GO_REF
neuropeptide hormone activity	ISO	GO_REF
neuropeptide hormone activity	IDA	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

vasopressin receptor binding [inference]

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

neuropeptide hormone activity

neurohypophyseal hormone activity

neuropeptide activity [inference]

neuropeptide hormone activity

neurohypophyseal hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

neuropeptide hormone activity

neurohypophyseal hormone activity

neuropeptide activity [inference]

neuropeptide hormone activity

neurohypophyseal hormone activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLAMMLNTTLSACFLSLLALTSACYFQNCPRGGKRATSDMELRQCLPCGPGGKGRCFGPSICCADELGCFLGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCSDESCVAEPECREGFFRLTRAREQSNATQLDGPARELLLRLVQLAGTQESVDSAKPRVY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
135	N-linked (GlcNAc...) asparagine	34106099	G88725PI	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Rattus norvegicus
Clathrin-mediated endocytosis	Rattus norvegicus
G alpha (q) signalling events	Rattus norvegicus
Transport of organic anions	Rattus norvegicus
Vasopressin regulates renal water homeostasis via Aquaporins	Rattus norvegicus
Vasopressin-like receptors	Rattus norvegicus

Disease

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:10762	portal hypertension	Alliance of Genome Resources
DOID:3328	temporal lobe epilepsy	Alliance of Genome Resources
DOID:4195	hyperglycemia	Alliance of Genome Resources
DOID:9409	diabetes insipidus	Alliance of Genome Resources
DOID:9744	type 1 diabetes mellitus	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements