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S-adenosylhomocysteine hydrolase

Summary

Gene Symbol

Ahcy

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

269378

KEGG Gene ID

PubChem

269378

Alliance of Genome Resources

MGI:87968

Annotation

Keyword

3D-structure
Acetylation
Copper
Cytoplasm
Endoplasmic reticulum
Hydrolase
Hydroxylation
NAD
Nucleus
One-carbon metabolism
Phosphoprotein
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q5M9P0
Q3TF14
P50247	CUBP Liver copper-binding protein S-adenosyl-L-homocysteine hydrolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
chronic inflammatory response to antigenic stimulus	ISO
modified amino acid metabolic process	IEA
one-carbon metabolic process
sulfur compound metabolic process	IEA
response to nutrient	ISO

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

inflammatory response to antigenic stimulus [inference]

chronic inflammatory response to antigenic stimulus

cellular process [inference]

metabolic process [inference]

modified amino acid metabolic process

S-methylmethionine metabolic process [inference]

S-methylmethionine cycle

sulfur compound metabolic process

S-methylmethionine metabolic process [inference]

S-methylmethionine cycle

S-adenosylmethionine metabolic process [inference]

L-methionine cycle

small molecule metabolic process [inference]

one-carbon metabolic process

multicellular organismal process [inference]

behavior [inference]

rhythmic behavior [inference]

circadian behavior [inference]

circadian sleep/wake cycle

rhythmic process [inference]

circadian rhythm [inference]

circadian behavior [inference]

circadian sleep/wake cycle

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

inflammatory response to antigenic stimulus [inference]

chronic inflammatory response to antigenic stimulus

chronic inflammatory response [inference]

chronic inflammatory response to antigenic stimulus

immune response [inference]

inflammatory response to antigenic stimulus [inference]

chronic inflammatory response to antigenic stimulus

response to nutrient levels [inference]

response to nutrient

response to chemical [inference]

response to nutrient

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	ISO
nucleus	IEA
cytoplasm	IEA
endoplasmic reticulum	ISS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
adenosylhomocysteinase activity	ISO
adenosylhomocysteinase activity	IDA
adenosylhomocysteinase activity	IBA
adenosylhomocysteinase activity	IEA
copper ion binding	IDA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on carbon-sulfur bonds [inference]

adenosylhomocysteinase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding

NAD binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

adenosylhomocysteinase A

Functional Category

E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 3** entries
Gene Ontology
S-adenosylmethionine cycle
adenosylhomocysteinase activity
hydrolase activity

Displaying **all 5** entries
InterPro
Adenosylhomocysteinase-like superfamily
Adenosylhomocysteinase-like
NAD(P)-binding domain superfamily
S-adenosyl-L-homocysteine hydrolase, NAD binding domain
S-adenosyl-L-homocysteine hydrolase, conserved site