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Adenosylhomocysteinase

Summary

UniProt ID: P50247
Gene Symbol: Ahcy
Gene ID: 269378
Organism: Mus musculus (house mouse)

External Links

GlyGen: P50247
PubChem: P50247
O-GlcNAcAtlas: P50247
Re-Glyco: P50247

Annotation

Keyword: 3D-structure Acetylation Copper Cytoplasm Endoplasmic reticulum Hydrolase Hydroxylation NAD Nucleus One-carbon metabolism Phosphoprotein Reference proteome

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
chronic inflammatory response to antigenic stimulus	ISO	GO_REF
one-carbon metabolic process
response to nutrient	ISO	GO_REF
obsolete S-adenosylhomocysteine catabolic process
L-methionine cycle	IBA	GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

inflammatory response to antigenic stimulus [inference]

chronic inflammatory response to antigenic stimulus

cellular process [inference]

metabolic process [inference]

modified amino acid metabolic process [inference]

S-methylmethionine metabolic process [inference]

S-methylmethionine cycle

sulfur compound metabolic process [inference]

S-methylmethionine metabolic process [inference]

S-methylmethionine cycle

S-adenosylmethionine metabolic process [inference]

L-methionine cycle

small molecule metabolic process [inference]

one-carbon metabolic process

multicellular organismal process [inference]

behavior [inference]

rhythmic behavior [inference]

circadian behavior [inference]

circadian sleep/wake cycle

rhythmic process [inference]

circadian rhythm [inference]

circadian behavior [inference]

circadian sleep/wake cycle

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

inflammatory response to antigenic stimulus [inference]

chronic inflammatory response to antigenic stimulus

chronic inflammatory response [inference]

chronic inflammatory response to antigenic stimulus

immune response [inference]

inflammatory response to antigenic stimulus [inference]

chronic inflammatory response to antigenic stimulus

response to nutrient levels [inference]

response to nutrient

response to chemical [inference]

response to nutrient

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GO Term	Evidence Code	Reference
nucleus	ISS	GO_REF
nucleus	ISO	GO_REF
nucleus	IEA	GO_REF
endoplasmic reticulum	ISS	GO_REF
endoplasmic reticulum	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

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GO Term	Evidence Code	Reference
adenosylhomocysteinase activity	ISO	GO_REF GO_REF
adenosylhomocysteinase activity	IDA	PMID PMID
adenosylhomocysteinase activity	IEA	GO_REF GO_REF GO_REF
copper ion binding	IDA	PMID
adenyl nucleotide binding	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on carbon-sulfur bonds [inference]

adenosylhomocysteinase activity

binding [inference]

protein binding [inference]

identical protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding

NAD binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding

NAD binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites