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Guidelines

MIRAGE

farnesyl diphosphate synthase

Summary

Gene Symbol

FDPS

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281156
KEGG Gene ID: bta:281156
PubChem: 281156

Annotation

Keyword

Acetylation
Cholesterol biosynthesis
Cytoplasm
Host-virus interaction
Hydroxylation
Isoprene biosynthesis
Magnesium
Metal-binding
Reference proteome
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8WMY2	(2E,6E)-farnesyl diphosphate synthase Dimethylallyltranstransferase Farnesyl diphosphate synthase Geranyltranstransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
farnesyl diphosphate biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying **all 2** entries
GO Term	Evidence Code	PMID
dimethylallyltranstransferase activity	IEA	30032202
geranyltranstransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring alkyl or aryl (other than methyl) groups [inference]

prenyltransferase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Farnesyl

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism

Displaying **all 4** entries
Gene Ontology
dimethylallyltranstransferase activity
farnesyl diphosphate biosynthetic process
geranyltranstransferase activity
transferase activity

Displaying **all 4** entries
InterPro
Farnesyl pyrophosphate synthase-like
Isoprenoid synthase domain superfamily
Polyprenyl synthetase, conserved site
Polyprenyl synthetase

KEGG BRITE Database

Orthology

K00787

Name

farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]

References

Rhea

isopentenyl diphosphate + (2E)-geranyl diphosphate

(2E,6E)-farnesyl diphosphate + diphosphate

Enzyme

2.5.1.10

PMID

isopentenyl diphosphate + dimethylallyl diphosphate

diphosphate + (2E)-geranyl diphosphate

Enzyme

2.5.1.1

PMID

Ortholog

Displaying entries **11 - 20** of 65 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Rattus norvegicus	100360417		RATNO25033
Callithrix jacchus	100386841		CALJA24952
Callithrix jacchus	100389801		CALJA39150
Callithrix jacchus	100392642		CALJA16747
Nomascus leucogenys	100598529		NOMLE05766
Loxodonta africana	100667894		LOXAF09426
Oreochromis niloticus	100706299		ORENI07114
Cavia porcellus	100717025		CAVPO06446
Cricetulus griseus	100754883		CRIGR08925
Sarcophilus harrisii	100931055		SARHA03611

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025