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Guidelines

MIRAGE

farnesyl diphosphate synthase

Summary

Gene Symbol

FDPS

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281156
KEGG Gene ID: bta:281156
PubChem: 281156

Annotation

Keyword

Acetylation
Cholesterol biosynthesis
Cytoplasm
Host-virus interaction
Hydroxylation
Isoprene biosynthesis
Magnesium
Metal-binding
Reference proteome
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8WMY2	(2E,6E)-farnesyl diphosphate synthase Dimethylallyltranstransferase Farnesyl diphosphate synthase Geranyltranstransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
farnesyl diphosphate biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying **all 2** entries
GO Term	Evidence Code	PMID
dimethylallyltranstransferase activity	IEA	30032202
geranyltranstransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring alkyl or aryl (other than methyl) groups [inference]

prenyltransferase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Farnesyl

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism

Displaying **all 4** entries
Gene Ontology
dimethylallyltranstransferase activity
farnesyl diphosphate biosynthetic process
geranyltranstransferase activity
transferase activity

Displaying **all 4** entries
InterPro
Farnesyl pyrophosphate synthase-like
Isoprenoid synthase domain superfamily
Polyprenyl synthetase, conserved site
Polyprenyl synthetase

KEGG BRITE Database

Orthology

K00787

Name

farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]

References

Rhea

isopentenyl diphosphate + (2E)-geranyl diphosphate

(2E,6E)-farnesyl diphosphate + diphosphate

Enzyme

2.5.1.10

PMID

isopentenyl diphosphate + dimethylallyl diphosphate

diphosphate + (2E)-geranyl diphosphate

Enzyme

2.5.1.1

PMID

Ortholog

Displaying entries **21 - 30** of 65 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Pan paniscus	100981763		PANPA02665
Papio anubis	101017660		PAPAN17840
Takifugu rubripes	101065291		TAKRU46991
Felis catus	101086533		FELCA37609
Gorilla gorilla gorilla	101130805		GORGO19150
Oryzias latipes	101157393		ORYLA05756
Tursiops truncatus	101331919		TURTR13544
Octodon degus	101560436		OCTDE06854
Jaculus jaculus	101606613		JACJA18986
Jaculus jaculus	101610267		JACJA18986

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025