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Guidelines

MIRAGE

interleukin 1 alpha

Summary

Gene Symbol

IL1A

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene

281250

KEGG Gene ID

PubChem

281250

Annotation

Keyword

Acetylation
Cytokine
Cytoplasm
Glycoprotein
Mitogen
Nucleus
Phosphoprotein
Pyrogen
Reference proteome
Secreted

Proteins

Displaying 1 entry
UniProt	Protein Name
P08831

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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2

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Last »
GO Term	Evidence Code	PMID
fever generation
apoptotic process	IEA
inflammatory response	IBA
inflammatory response	IEA
immune response	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

heat generation [inference]

fever generation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

heat generation [inference]

fever generation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

acute inflammatory response [inference]

acute-phase response [inference]

fever generation

response to heat [inference]

cellular response to heat

cellular response to stress [inference]

cellular response to heat

immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat [inference]

cellular response to heat

response to chemical [inference]

response to metal ion [inference]

response to copper ion

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell division

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of interleukin-2 production [inference]

positive regulation of interleukin-2 production

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of interleukin-2 production [inference]

positive regulation of interleukin-2 production

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell division

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of cell division [inference]

positive regulation of cell division

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of interleukin-2 production [inference]

positive regulation of interleukin-2 production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of oxidoreductase activity [inference]

regulation of nitric-oxide synthase activity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
obsolete extracellular space
nucleus	ISS
nucleus	IEA
cytosol	ISS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytokine activity	IBA
cytokine activity	IEA
interleukin-1 receptor binding	IEA
copper ion binding	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

interleukin-1 receptor binding

growth factor receptor binding [inference]

interleukin-1 receptor binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

interleukin-1 alpha

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 10** entries
Gene Ontology
cellular response to lipopolysaccharide
cytokine activity
cytokine-mediated signaling pathway
fever generation
immune response
inflammatory response
interleukin-1 receptor binding
positive regulation of cell division
positive regulation of gene expression
positive regulation of immature T cell proliferation in thymus

Displaying **all 5** entries
InterPro
Cytokine IL1/FGF
Interleukin-1 alpha
Interleukin-1 conserved site
Interleukin-1 family
Interleukin-1 propeptide

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026