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MIRAGE

Interleukin-1 alpha

Summary

UniProt ID: P08831
Gene Symbol: IL1A
Gene ID: 281250
Organism: Bos taurus (domestic cattle)

External Links

PubChem: P08831
Re-Glyco: P08831

Annotation

Keyword: Acetylation Cytokine Cytoplasm Glycoprotein Mitogen Nucleus Phosphoprotein Pyrogen Reference proteome Secreted

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
fever generation
apoptotic process	IEA	GO_REF
inflammatory response	IBA	GO_REF
inflammatory response	IEA	GO_REF
immune response	IBA	GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

heat generation [inference]

fever generation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

heat generation [inference]

fever generation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

acute inflammatory response [inference]

acute-phase response [inference]

fever generation

response to heat [inference]

cellular response to heat

cellular response to stress [inference]

cellular response to heat

immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat [inference]

cellular response to heat

response to chemical [inference]

response to metal ion [inference]

response to copper ion

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell division

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of interleukin-2 production [inference]

positive regulation of interleukin-2 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of interleukin-2 production [inference]

positive regulation of interleukin-2 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell division

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of cell division [inference]

positive regulation of cell division

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

regulation of interleukin-2 production [inference]

positive regulation of interleukin-2 production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

regulation of immature T cell proliferation [inference]

regulation of immature T cell proliferation in thymus [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-2 production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation [inference]

positive regulation of immature T cell proliferation [inference]

positive regulation of immature T cell proliferation in thymus

Displaying **all 4** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
nucleus	ISS	GO_REF
nucleus	IEA	GO_REF
cytosol	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 4** entries
GO Term	Evidence Code	Reference
cytokine activity	IBA	GO_REF
cytokine activity	IEA	GO_REF GO_REF
interleukin-1 receptor binding	IEA	GO_REF
copper ion binding	ISS	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

interleukin-1 receptor binding

growth factor receptor binding [inference]

interleukin-1 receptor binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAKVPDLFEDLKNCYSENEDYSSEIDHLSLNQKSFYDASYEPLREDQMNKFMSLDTSETSKTSKLSFKENVVMVAASGKILKKRRLSLNQFITDDDLEAIANNTEEEIIKPRSAHYSFQSNVKYNFMRVIHQECILNDALNQSIIRDMSGPYLTATTLNNLEEAVKFDMVAYVSEEDSQLPVTLRISKTQLFVSAQNEDEPVLLKEMPETPKIIKDETNLLFFWEKHGSMDYFKSVAHPKLFIATKQEKLVHMASGPPSITDFQILEK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
102	N-linked (GlcNAc...) asparagine			UniProt
141	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Interleukin-1 processing	Bos taurus
Interleukin-1 signaling	Bos taurus
Pyroptosis	Bos taurus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026