GlyCosmos Portal

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Disease variant
NAD
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P21695
A0A024R138

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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2

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GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
glycerol-3-phosphate metabolic process	IBA
glycerol-3-phosphate metabolic process	IEA
gluconeogenesis
glycerol-3-phosphate shuttle

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process

glycerol-3-phosphate catabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

organophosphate catabolic process [inference]

glycerol-3-phosphate catabolic process

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process

glycerol-3-phosphate catabolic process

catabolic process [inference]

organophosphate catabolic process [inference]

glycerol-3-phosphate catabolic process

carbohydrate derivative catabolic process [inference]

glycerol-3-phosphate catabolic process

biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

primary metabolic process [inference]

carbohydrate metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

glycerol-3-phosphate shuttle

carbohydrate derivative metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process

glycerol-3-phosphate catabolic process

carbohydrate derivative catabolic process [inference]

glycerol-3-phosphate catabolic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

response to stimulus [inference]

response to chemical [inference]

response to organophosphorus [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

response to peptide [inference]

response to cytokine [inference]

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

response to nitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to nitrogen compound [inference]

cellular response to cAMP

response to oxygen-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glycolytic process

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of cellular process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glycolytic process

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

regulation of nucleotide catabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

regulation of carbohydrate catabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

regulation of phosphorus metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of carbohydrate catabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glycolytic process

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glycolytic process

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide catabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide catabolic process [inference]

positive regulation of glycolytic process

positive regulation of ATP metabolic process [inference]

positive regulation of glycolytic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA
cytosol	TAS
cytosol	IBA
cytosol	IEA
extracellular exosome	HDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA
protein homodimerization activity	IEA
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IBA
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

glycerol-3-phosphate dehydrogenase [NAD(P)+] activity

glycerol-3-phosphate dehydrogenase (NAD+) activity

binding [inference]

protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000167588

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K00006

Name

glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]

References

8196651

Rhea

RHEA:11092

NAD⁺ + sn-glycerol 3-phosphate

H⁺ + dihydroxyacetone phosphate + NADH

Enzyme

PMID

Disease

The Human Phenotype Ontology

Displaying entries **1 - 10** of 11 in total

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HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0001395	Hepatic fibrosis
HP:0001397	Hepatic steatosis
HP:0001508	Failure to thrive
HP:0001744	Splenomegaly
HP:0002013	Vomiting
HP:0002155	Hypertriglyceridemia
HP:0002240	Hepatomegaly
HP:0002910	Elevated circulating hepatic transaminase concentration
HP:0003593	Infantile onset

Displaying 1 entry
Disease ID	Disease Name
OMIM:614480	transient infantile hypertriglyceridemia and hepatosteatosis

PubChem Disease

MedGen Diseases

Transient infantile hypertriglyceridemia and hepatosteatosis

OMIM Phenotypes

HYPERTRIGLYCERIDEMIA, TRANSIENT INFANTILE; HTGTI

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP001364
Gene Name: glycerol-3-phosphate dehydrogenase 1 (soluble)

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	14555	MGI:95679
Rattus norvegicus	60666	RGD:621381
Caenorhabditis elegans	176399	WB:WBGene00010778
Drosophila melanogaster	33824	FB:FBgn0001128
Saccharomyces cerevisiae S288C	851539	SGD:S000002180
Saccharomyces cerevisiae S288C	854095	SGD:S000005420

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements