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glycerol-3-phosphate dehydrogenase (NAD(+)) GPD1

Summary

Gene Symbol

GPD1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

851539

KEGG Gene ID

sce:YDL022W

PubChem

851539

Alliance of Genome Resources

SGD:S000002180

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
Direct protein sequencing
NAD
Oxidoreductase
Peroxisome
Phosphoprotein
Reference proteome
Stress response

Proteins

Displaying 1 entry
UniProt	Protein Name
Q00055

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
glycerol-3-phosphate metabolic process	IBA
glycerol-3-phosphate metabolic process	IEA
intracellular accumulation of glycerol	IMP
protein import into peroxisome matrix	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process

glycerol-3-phosphate catabolic process

organophosphate metabolic process [inference]

organophosphate catabolic process [inference]

glycerol-3-phosphate catabolic process

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process

glycerol-3-phosphate catabolic process

catabolic process [inference]

organophosphate catabolic process [inference]

glycerol-3-phosphate catabolic process

carbohydrate derivative catabolic process [inference]

glycerol-3-phosphate catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

carbohydrate derivative metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process

glycerol-3-phosphate catabolic process

carbohydrate derivative catabolic process [inference]

glycerol-3-phosphate catabolic process

intercellular transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

protein import into peroxisome matrix

transmembrane transport [inference]

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

peroxisome organization [inference]

protein localization to peroxisome [inference]

protein import into peroxisome matrix

homeostatic process [inference]

cellular homeostasis [inference]

intracellular accumulation of glycerol

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

protein localization to peroxisome [inference]

protein import into peroxisome matrix

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

protein import into peroxisome matrix

transmembrane transport [inference]

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

establishment of protein localization to peroxisome [inference]

protein import into peroxisome matrix

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

protein import into peroxisome matrix

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into peroxisome matrix

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

protein import into peroxisome matrix

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
nucleus	IDA
nucleus	IBA
cytoplasm	IEA
mitochondrion	HDA
peroxisome	EXP

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA
protein homodimerization activity	IEA
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	RCA
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IMP
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

glycerol-3-phosphate dehydrogenase [NAD(P)+] activity

glycerol-3-phosphate dehydrogenase (NAD+) activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00006

Name

glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]

References

8196651

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
cytosol	PMID:15210723
nucleus	PMID:20026609
peroxisome	PMID:15210723
mitochondrion	PMID:24769239

Rhea

RHEA:11092

NAD⁺ + sn-glycerol 3-phosphate

H⁺ + dihydroxyacetone phosphate + NADH

Enzyme

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007447
Gene Name: glycerol-3-phosphate dehydrogenase (NAD(+)) GPD1

Ortholog

Displaying **all 9** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	14555	MGI:95679
Mus musculus	333433	MGI:1289257
Rattus norvegicus	60666	RGD:621381
Caenorhabditis elegans	176399	WB:WBGene00010778
Drosophila melanogaster	33824	FB:FBgn0001128
Homo sapiens	23171	HGNC:28956
Homo sapiens	2819	HGNC:4455
Danio rerio	449663	ZFIN:ZDB-GENE-041010-220
Xenopus tropicalis	394623	Xenbase:XB-GENE-969902