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AKT serine/threonine kinase 3

Summary

Gene Symbol

Akt3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29414

KEGG Gene ID

PubChem

29414

Alliance of Genome Resources

RGD:62390

Annotation

Keyword

ATP-binding
Acetylation
Cytoplasm
Disulfide bond
Glycoprotein
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q63484	Protein kinase Akt-3 Protein kinase B gamma RAC-PK-gamma

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
positive regulation of endothelial cell proliferation	ISO
protein phosphorylation	IDA
signal transduction	ISO
insulin receptor signaling pathway	IBA
positive regulation of sodium ion transport	IMP

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

intracellular signal transduction

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

positive regulation of cell size

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

brain morphogenesis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to chemical [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

positive regulation of TOR signaling

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

positive regulation of sodium ion transport

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

regulation of cell migration involved in sprouting angiogenesis [inference]

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation

positive regulation of vascular endothelial cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of artery morphogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of cellular senescence

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

positive regulation of TOR signaling

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

regulation of artery morphogenesis [inference]

positive regulation of artery morphogenesis

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of artery morphogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

intracellular signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

positive regulation of TOR signaling

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation

positive regulation of vascular endothelial cell proliferation

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation [inference]

positive regulation of endothelial cell proliferation

positive regulation of vascular endothelial cell proliferation

regulation of vascular endothelial cell proliferation [inference]

positive regulation of vascular endothelial cell proliferation

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation

positive regulation of vascular endothelial cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation

positive regulation of vascular endothelial cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of cellular senescence

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of mitochondrion organization

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

regulation of cell migration involved in sprouting angiogenesis [inference]

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration involved in sprouting angiogenesis

regulation of cellular senescence [inference]

negative regulation of cellular senescence

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

positive regulation of cell size

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GO Term	Evidence Code	PMID
nucleus	IEA
nucleoplasm	ISO
nucleoplasm	TAS
cytoplasm	IEA
Golgi apparatus

GO Hierarchy

cellular component

cellular anatomical structure [inference]

microtubule organizing center [inference]

ciliary basal body

cytosol

membrane

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
protein kinase activity	IEA
protein serine/threonine kinase activity	ISO
protein serine/threonine kinase activity	IDA
protein serine/threonine kinase activity	IBA
protein serine/threonine kinase activity	IEA