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RAC-gamma serine/threonine-protein kinase

Summary

UniProt ID

Q63484

Gene Symbol

Akt3

Gene ID

29414

Organism

Rattus norvegicus (Norway rat)

External Links

Re-Glyco: Q63484

Annotation

Keyword

ATP-binding
Acetylation
Cytoplasm
Disulfide bond
Glycoprotein
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
membrane
nucleoplasm
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
positive regulation of artery morphogenesis
positive regulation of endothelial cell proliferation
positive regulation of sodium ion transport
positive regulation of TOR signaling
cellular response to insulin stimulus
positive regulation of blood vessel endothelial cell migration
positive regulation of cell size
brain morphogenesis
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of vascular endothelial cell proliferation

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GO Term
histone H3T3 kinase activity
histone H2AT120 kinase activity
histone H4S1 kinase activity
histone H2AS121 kinase activity
DNA-dependent protein kinase activity
histone H2AXS139 kinase activity
histone H2BS14 kinase activity
histone H2BS36 kinase activity
histone H3T45 kinase activity
histone H3S57 kinase activity

Annotation information from UniProt.

Sequence

MSDVTIVKEDWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDPKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKDDDDGMDCMDNERRPHFPQFSYSASGRE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
302	O-linked (GlcNAc) threonine	UniProt
309	O-linked (GlcNAc) threonine	UniProt
472		UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
AKT phosphorylates targets in the cytosol	Rattus norvegicus
AKT phosphorylates targets in the nucleus	Rattus norvegicus
AKT-mediated inactivation of FOXO1A	Rattus norvegicus
CD28 dependent PI3K/Akt signaling	Rattus norvegicus
CTLA4 inhibitory signaling	Rattus norvegicus
Cyclin A:Cdk2-associated events at S phase entry	Rattus norvegicus
Cyclin E associated events during G1/S transition	Rattus norvegicus
Downregulation of ERBB2:ERBB3 signaling	Rattus norvegicus
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Rattus norvegicus
FLT3 Signaling	Rattus norvegicus

GlyTouCan

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UniCarb-DR

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Annotation

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Acknowledgements