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opsin 4 (melanopsin)

Summary

Gene Symbol

Opn4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

30044

KEGG Gene ID

PubChem

30044

Alliance of Genome Resources

MGI:1353425

Annotation

Keyword

Alternative splicing
Biological rhythms
Cell membrane
Cell projection
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Retinal protein
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9QXZ9	Opsin-4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 29 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IBA
G protein-coupled receptor signaling pathway	IEA
adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

phototransduction

G protein-coupled opsin signaling pathway

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

behavior [inference]

visual behavior [inference]

optokinetic behavior

developmental process [inference]

anatomical structure development [inference]

retina development in camera-type eye

anatomical structure regression [inference]

hyaloid vascular plexus regression

locomotion [inference]

taxis [inference]

thermotaxis

rhythmic process

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

G protein-coupled opsin signaling pathway

detection of visible light

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

thermotaxis

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

optokinetic behavior

detection of light stimulus [inference]

phototransduction

G protein-coupled opsin signaling pathway

detection of visible light

photoperiodism [inference]

entrainment of circadian clock by photoperiod

cellular response to light stimulus

G protein-coupled opsin signaling pathway

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

G protein-coupled opsin signaling pathway

detection of visible light

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

G protein-coupled opsin signaling pathway

detection of visible light

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

G protein-coupled opsin signaling pathway

detection of visible light

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

detection of stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of circadian rhythm

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of circadian rhythm [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of biological process [inference]

positive regulation of circadian rhythm [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

phototransduction

G protein-coupled opsin signaling pathway

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	EXP
plasma membrane	IDA
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

sperm head plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

perikaryon

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor activity	ISO
G protein-coupled receptor activity	IEA
11-cis retinal binding	ISS
11-cis retinal binding	ISO
11-cis retinal binding	IEA

GO Hierarchy

molecular function

binding [inference]

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinal binding [inference]

11-cis retinal binding

small molecule binding [inference]

vitamin binding [inference]

retinal binding [inference]

11-cis retinal binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled photoreceptor activity

photoreceptor activity [inference]

G protein-coupled photoreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	192223	RGD:621701
Drosophila melanogaster	42367	FB:FBgn0002940
Drosophila melanogaster	42261	FB:FBgn0003248
Drosophila melanogaster	34615	FB:FBgn0014019
Drosophila melanogaster	42398	FB:FBgn0003249
Drosophila melanogaster	41889	FB:FBgn0019940
Drosophila melanogaster	39887	FB:FBgn0003250
Danio rerio	352918	ZFIN:ZDB-GENE-030314-2