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ectonucleotide pyrophosphatase/phosphodiesterase 7

Summary

Gene Symbol

Enpp7

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

303729

KEGG Gene ID

PubChem

303729

Alliance of Genome Resources

RGD:1359324

Annotation

Keyword

Cell membrane
Direct protein sequencing
Glycoprotein
Hydrolase
Lipid metabolism
Metal-binding
Reference proteome
Signal
Transmembrane helix
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0ABK0LU73
Q5EZ72	Alkaline sphingomyelin phosphodiesterase Intestinal alkaline sphingomyelinase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
sphingomyelin metabolic process	ISS
sphingomyelin metabolic process	ISO
negative regulation of DNA replication	ISO
negative regulation of cell population proliferation	ISO
lipid digestion	ISS

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process

sphingolipid metabolic process [inference]

sphingomyelin metabolic process

multicellular organismal process [inference]

digestion [inference]

lipid digestion

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

fatty acid homeostasis

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of lipid catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of phospholipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of sphingomyelin catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of sphingomyelin catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

negative regulation of DNA replication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of lipid catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of phospholipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of sphingomyelin catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of sphingomyelin catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

negative regulation of DNA replication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

regulation of cellular component biogenesis [inference]

regulation of sphingolipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of sphingolipid biosynthetic process [inference]

positive regulation of ceramide biosynthetic process

positive regulation of lipid catabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid catabolic process [inference]

positive regulation of sphingomyelin catabolic process

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of digestive system process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

regulation of intestinal absorption [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

regulation of intestinal lipid absorption

regulation of intestinal cholesterol absorption [inference]

positive regulation of intestinal cholesterol absorption

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
Golgi apparatus	ISO
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	EXP
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
sphingomyelin phosphodiesterase activity	ISS
sphingomyelin phosphodiesterase activity	ISO
sphingomyelin phosphodiesterase activity	EXP
sphingomyelin phosphodiesterase activity	IDA
sphingomyelin phosphodiesterase activity	IEA