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vesicle-associated membrane protein, associated protein A

Summary

Gene Symbol

Vapa

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

30960

PubChem

30960

Alliance of Genome Resources

MGI:1353561

Annotation

Keyword

3D-structure
Acetylation
Cell membrane
Coiled coil
Direct protein sequencing
Disulfide bond
Endoplasmic reticulum
Nucleus
Phosphoprotein
Reference proteome
Tight junction
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9WV55	33 kDa VAMP-associated protein

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
sphingomyelin biosynthetic process	ISO
sphingomyelin biosynthetic process	IEA
endoplasmic reticulum to Golgi vesicle-mediated transport	ISO
endoplasmic reticulum to Golgi vesicle-mediated transport	IEA
phospholipid transport	ISO

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

sphingolipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

sphingolipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

sphingolipid biosynthetic process [inference]

sphingomyelin biosynthetic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

sphingolipid biosynthetic process [inference]

sphingomyelin biosynthetic process

intercellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

membrane docking [inference]

organelle localization by membrane tethering [inference]

endoplasmic reticulum-plasma membrane tethering

cellular localization [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle budding from membrane [inference]

COPII-coated vesicle budding

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

membrane organization [inference]

vesicle budding from membrane [inference]

COPII-coated vesicle budding

viral process [inference]

viral release from host cell

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

host-mediated perturbation of symbiont process [inference]

host-mediated perturbation of viral process [inference]

host-mediated activation of viral process [inference]

host-mediated activation of viral genome replication

host-mediated perturbation of viral genome replication [inference]

host-mediated activation of viral genome replication

host-mediated suppression of viral genome replication

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

exit from host cell [inference]

viral release from host cell

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum

establishment of localization [inference]

transport [inference]

lipid transport [inference]

phospholipid transport

sterol transport

cholesterol transport

ceramide transport

intercellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

organophosphate ester transport [inference]

phospholipid transport

organic hydroxy compound transport [inference]

sterol transport

cholesterol transport

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

nitrogen compound transport [inference]

ceramide transport

establishment of localization in cell [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

organelle localization [inference]

endoplasmic reticulum localization [inference]

endoplasmic reticulum-plasma membrane tethering

organelle localization by membrane tethering [inference]

endoplasmic reticulum-plasma membrane tethering

cellular localization [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
Golgi membrane	ISO
Golgi membrane	IEA
endoplasmic reticulum	ISO
endoplasmic reticulum	IDA
endoplasmic reticulum	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular membraneless organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
microtubule binding	ISO
microtubule binding	IEA
protein domain specific binding	ISO
protein domain specific binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

protein domain specific binding

FFAT motif binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein-containing complex binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

protein-membrane adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

vesicle-associated membrane -associated A

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
FFAT motif binding
endoplasmic reticulum membrane organization
endoplasmic reticulum-plasma membrane tethering

Displaying **all 4** entries
InterPro
Immunoglobulin-like fold
Major sperm protein (MSP) domain
PapD-like superfamily
Vesicle-associated membrane-protein-associated protein

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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