GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

nicotinamide nucleotide transhydrogenase

Summary

Gene Symbol

Nnt

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

310378

KEGG Gene ID

PubChem

310378

Alliance of Genome Resources

RGD:1587346

Annotation

Keyword

Acetylation
Mitochondrion inner membrane
NAD
NADP
Proteomics identification
Reference proteome
Transit peptide
Translocase
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A8I6AC81	Nicotinamide nucleotide transhydrogenase Pyridine nucleotide transhydrogenase
A0A8I6A0P0
Q5BJZ3	Nicotinamide nucleotide transhydrogenase Pyridine nucleotide transhydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
NADPH regeneration	IMP
NADPH regeneration	IBA
positive regulation of mitochondrial membrane potential	IMP
intracellular oxygen homeostasis	IMP
response to vitamin	IEP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy [inference]

NADPH regeneration

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration

reactive oxygen species metabolic process

cellular detoxification [inference]

cellular oxidant detoxification

homeostatic process [inference]

cellular homeostasis [inference]

cell redox homeostasis

intracellular chemical homeostasis [inference]

intracellular oxygen homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular oxygen homeostasis

response to stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin

response to chemical [inference]

response to nutrient [inference]

response to vitamin

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

regulation of hydrogen peroxide catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

regulation of reactive oxygen species metabolic process [inference]

regulation of hydrogen peroxide metabolic process [inference]

regulation of hydrogen peroxide catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of biological quality [inference]

regulation of membrane potential [inference]

positive regulation of membrane potential [inference]

positive regulation of mitochondrial membrane potential

regulation of mitochondrial membrane potential [inference]

positive regulation of mitochondrial membrane potential

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrial inner membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proton-translocating NAD(P)+ transhydrogenase activity	IEA
oxidoreductase activity	IEA
NADP binding	ISO
NADP binding	IBA
NADP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton-translocating NAD(P)+ transhydrogenase activity

active monoatomic ion transmembrane transporter activity [inference]

proton-translocating NAD(P)+ transhydrogenase activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

oxidoreduction-driven active transmembrane transporter activity [inference]

proton-translocating NAD(P)+ transhydrogenase activity

active monoatomic ion transmembrane transporter activity [inference]

proton-translocating NAD(P)+ transhydrogenase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	23530	HGNC:7863

About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: [email protected]

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026