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Glycan Structure Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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MIRAGE
major histocompatibility complex, class II, DR alpha
Summary
- Gene Symbol
-
- HLA-DRA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Host-virus interaction
- Isopeptide bond
- Lysosome
- MHC II
- Proteomics identification
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0G2JMH6 |
|
| P01903 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of T cell mediated cytotoxicity |
|
|
| adaptive immune response |
|
|
| myeloid dendritic cell antigen processing and presentation |
|
|
| antigen processing and presentation of endogenous peptide antigen via MHC class II |
|
|
| peptide antigen assembly with MHC class II protein complex |
|
GO Hierarchy
biological process
immune system process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
regulation of alpha-beta T cell differentiation [inference]
regulation of CD4-positive, alpha-beta T cell activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of cellular process [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of cell differentiation [inference]
regulation of cell development [inference]
positive regulation of cell development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
regulation of cellular process [inference]
regulation of cell adhesion [inference]
regulation of cell differentiation [inference]
positive regulation of cell differentiation [inference]
regulation of cell development [inference]
positive regulation of cell development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
regulation of alpha-beta T cell differentiation [inference]
regulation of CD4-positive, alpha-beta T cell activation [inference]
positive regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
regulation of alpha-beta T cell differentiation [inference]
regulation of CD4-positive, alpha-beta T cell activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane |
|
|
| immunological synapse |
|
|
| lysosome |
|
|
| lysosomal membrane |
|
|
| lysosomal membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding |
|
|
| MHC class II protein complex binding |
|
|
| MHC class II protein complex binding |
|
|
| polysaccharide binding |
|
|
| peptide antigen binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- HLA class II histocompatibility antigen, DO alpha chain
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| adaptive immune response |
| antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
| immune response |
| immune system process |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060892 | late onset Parkinson's disease | |
| DOID:1205 | allergic disease | |
| DOID:14330 | Parkinson's disease | |
| DOID:2377 | multiple sclerosis | |
| DOID:2841 | asthma | |
| DOID:7188 | autoimmune thyroiditis |
