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FIG4 phosphoinositide 5-phosphatase

Summary

Gene Symbol

FIG4

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

33658

KEGG Gene ID

dme:Dmel_CG17840

PubChem

33658

Alliance of Genome Resources

FB:FBgn0031611

Annotation

Keyword

Hydrolase
Membrane
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VR06

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
phosphatidylinositol-3-phosphate biosynthetic process	IEA
phosphatidylinositol metabolic process	IEA
phosphatidylinositol dephosphorylation	IBA
phosphatidylinositol dephosphorylation	IEA
regulation of lysosome organization	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol dephosphorylation

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol dephosphorylation

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

lipid modification [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol dephosphorylation

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of vacuole organization [inference]

regulation of lysosome organization

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endosome membrane	ISS
endomembrane system	IEA
intracellular membrane-bounded organelle	IBA
PAS complex	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

PAS complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

PAS complex

cellular anatomical structure [inference]

endomembrane system

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying **all 4** entries
GO Term	Evidence Code	PMID
phosphatase activity	IEA
phosphatidylinositol bisphosphate phosphatase activity	ISS
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	IBA
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

phosphatidylinositol phosphate phosphatase activity [inference]

phosphatidylinositol bisphosphate phosphatase activity

phosphatidylinositol-3,5-bisphosphate phosphatase activity [inference]

phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

phosphatidylinositol phosphate 5-phosphatase activity [inference]

phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K22913

Name

phosphatidylinositol 3,5-bisphosphate 5-phosphatase [EC:3.1.3.-]

References

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:10595	Charcot-Marie-Tooth disease	Alliance of Genome Resources
DOID:0060202	amyotrophic lateral sclerosis type 11	Alliance of Genome Resources
DOID:1289	neurodegenerative disease	Alliance of Genome Resources
DOID:0110184	Charcot-Marie-Tooth disease type 4J	Alliance of Genome Resources