GlyCosmos Portal

Annotation

Keyword

Hydrolase
Membrane
Phosphoprotein
Reference proteome
Vacuole

Proteins

Displaying 1 entry
UniProt	Protein Name
P42837	Factor-induced gene 4 protein Phosphatidylinositol 3,5-bisphosphate 5-phosphatase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
regulation of phosphatidylinositol biosynthetic process	NAS
phosphatidylinositol-3-phosphate biosynthetic process	IEA
phosphatidylinositol dephosphorylation	IDA
phosphatidylinositol dephosphorylation	IGI
phosphatidylinositol dephosphorylation	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

dephosphorylation [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

lipid modification [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of phosphatidylinositol biosynthetic process

regulation of phosphorus metabolic process [inference]

regulation of phosphatidylinositol biosynthetic process

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
fungal-type vacuole membrane	IDA
vacuolar membrane	IEA
nuclear periphery	IDA
intracellular membrane-bounded organelle	IBA
PAS complex	NAS

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

PAS complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

PAS complex

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane

lytic vacuole membrane [inference]

fungal-type vacuole membrane

nuclear periphery

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
phosphatase activity	IEA
phosphatidylinositol bisphosphate phosphatase activity	IEA
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	RCA
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	IDA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

phosphatidylinositol phosphate phosphatase activity [inference]

phosphatidylinositol bisphosphate phosphatase activity

phosphatidylinositol-3,5-bisphosphate phosphatase activity [inference]

phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

phosphatidylinositol phosphate 5-phosphatase activity [inference]

phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K22913

Name

phosphatidylinositol 3,5-bisphosphate 5-phosphatase [EC:3.1.3.-]

References

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
fungal-type vacuole membrane	PMID:14528018
PAS complex	PMID:19037259
nuclear periphery	PMID:25817432

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0060589	Yunis-Varon syndrome	Alliance of Genome Resources
DOID:0060202	amyotrophic lateral sclerosis type 11	Alliance of Genome Resources
DOID:0080923	bilateral parasagittal parieto-occipital polymicrogyria	Alliance of Genome Resources
DOID:0110184	Charcot-Marie-Tooth disease type 4J	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007276
Gene Name: phosphatidylinositol-3,5-bisphosphate 5-phosphatase

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	33658	FB:FBgn0031611
Homo sapiens	9896	HGNC:16873

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Guidelines

Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements