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Guidelines

MIRAGE

ankyrin 3

Summary

Gene Symbol

Ank3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

361833

KEGG Gene ID

PubChem

361833

Alliance of Genome Resources

RGD:620157

Annotation

Keyword

3D-structure
ANK repeat
Alternative splicing
Cell membrane
Cell projection
Cytoplasm
Cytoskeleton
Lysosome
Membrane
Phosphoprotein
Postsynaptic cell membrane
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A8I6A9I9
O70511	Ankyrin-G
A6JKS6
A6JKS7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 52 in total

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GO Term	Evidence Code	PMID
mitotic cytokinesis	ISO
regulation of transcription by RNA polymerase II	IBA
plasma membrane organization	ISO
signal transduction	IEA
axonogenesis	ISO

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

establishment or maintenance of microtubule cytoskeleton polarity

microtubule-based movement [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

establishment or maintenance of cell polarity [inference]

establishment or maintenance of cytoskeleton polarity [inference]

establishment or maintenance of microtubule cytoskeleton polarity

signal transduction

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis [inference]

mitotic cytokinesis

mitotic cell cycle process [inference]

mitotic cytokinesis

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

maintenance of location in cell [inference]

maintenance of protein location in cell

maintenance of protein location in membrane [inference]

maintenance of protein location in plasma membrane

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

establishment or maintenance of microtubule cytoskeleton polarity

establishment or maintenance of cytoskeleton polarity [inference]

establishment or maintenance of microtubule cytoskeleton polarity

cellular component assembly [inference]

membrane assembly

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

axon development

neuron projection guidance [inference]

axon guidance

cell junction organization [inference]

synapse organization

neuromuscular junction development

membrane organization [inference]

plasma membrane organization

neuronal ion channel clustering [inference]

clustering of voltage-gated sodium channels

membrane assembly

developmental process [inference]

anatomical structure morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

homeostatic process [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

magnesium ion homeostasis

inorganic ion homeostasis [inference]

magnesium ion homeostasis

response to stimulus [inference]

response to stress [inference]

response to immobilization stress

response to chemical [inference]

response to metal ion [inference]

response to magnesium ion [inference]

cellular response to magnesium ion

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane

Golgi to plasma membrane protein transport

protein localization to axon

protein localization to cell periphery [inference]

protein localization to plasma membrane

Golgi to plasma membrane protein transport

establishment of localization [inference]

transport [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

establishment of protein localization

protein transport [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell

maintenance of protein location in membrane [inference]

maintenance of protein location in plasma membrane

maintenance of location in cell [inference]

maintenance of protein location in cell

maintenance of protein location in membrane [inference]

maintenance of protein location in plasma membrane

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of delayed rectifier potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of monoatomic cation transmembrane transport

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of sodium ion import across plasma membrane [inference]

positive regulation of sodium ion import across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

positive regulation of sodium ion transport

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of sodium ion import across plasma membrane [inference]

positive regulation of sodium ion import across plasma membrane

regulation of potassium ion transport

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of monoatomic cation transmembrane transport

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of sodium ion import across plasma membrane [inference]

positive regulation of sodium ion import across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

regulation of cellular localization [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cell communication by electrical coupling

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

positive regulation of protein targeting to membrane

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of membrane depolarization [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of endocytosis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

regulation of cellular process [inference]

regulation of membrane depolarization [inference]

regulation of membrane depolarization during action potential [inference]

regulation of membrane depolarization during cardiac muscle cell action potential [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

positive regulation of membrane depolarization [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cell communication by electrical coupling

regulation of cell communication by electrical coupling [inference]

positive regulation of cell communication by electrical coupling

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

regulation of homotypic cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of delayed rectifier potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of monoatomic cation transmembrane transport

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

regulation of sodium ion import across plasma membrane [inference]

positive regulation of sodium ion import across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cell communication by electrical coupling

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion import across plasma membrane

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

positive regulation of protein targeting to membrane

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

regulation of synapse organization [inference]

regulation of modification of synaptic structure [inference]

regulation of modification of postsynaptic structure

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

regulation of cellular localization [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

regulation of biological quality [inference]

regulation of membrane potential [inference]

action potential [inference]

neuronal action potential

regulation of membrane depolarization [inference]

regulation of membrane depolarization during action potential [inference]

regulation of membrane depolarization during cardiac muscle cell action potential [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

positive regulation of membrane depolarization [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

positive regulation of membrane potential

regulation of molecular function [inference]

regulation of transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of delayed rectifier potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of molecular function [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

Displaying entries **1 - 5** of 54 in total

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GO Term	Evidence Code	PMID
nucleus	IBA
cytoplasm
lysosome	ISS
lysosome	IEA
cytoskeleton	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

neuron projection cytoplasm [inference]

axon cytoplasm

cell surface

plasma membrane

sarcolemma

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

cell-cell contact zone [inference]

intercalated disc

tight junction [inference]

bicellular tight junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum [inference]

sarcoplasmic reticulum

membraneless organelle [inference]

intracellular membraneless organelle [inference]

spectrin-associated cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum [inference]

sarcoplasmic reticulum

intracellular membraneless organelle [inference]

spectrin-associated cytoskeleton

postsynaptic specialization [inference]

postsynaptic density

postsynapse

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
structural constituent of cytoskeleton	ISO
protein binding	IPI
cytoskeletal protein binding	IBA
cytoskeletal protein binding	IPI
sodium channel regulator activity	IDA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of cytoskeleton

binding [inference]

protein binding

cytoskeletal protein binding

spectrin binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding

transmembrane transporter binding

cell adhesion molecule binding [inference]

cadherin binding

modification-dependent protein binding [inference]

phosphorylation-dependent protein binding

protein-containing complex binding [inference]

spectrin binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

molecular function regulator activity [inference]

molecular function activator activity [inference]

transporter activator activity [inference]

channel activator activity

transporter regulator activity [inference]

channel regulator activity [inference]

channel activator activity

ion channel regulator activity [inference]

sodium channel regulator activity

transporter activator activity [inference]

channel activator activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying entries **1 - 10** of 11 in total

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Location	References
axon	PMID:17709431
postsynaptic membrane	PMID:11796721 PMID:9664041
intercalated disc	PMID:20467587
Z disc	PMID:9664041
costamere	PMID:11171381
axon initial segment	PMID:21551097
dendrite	PMID:18786578
sarcolemma	PMID:11796721 PMID:15953600
sarcoplasmic reticulum	PMID:9664041
node of Ranvier	PMID:17548513 PMID:17709431

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	11735	MGI:88026
Homo sapiens	288	HGNC:494

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Last updated: April 6, 2026