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Repository for lectin-assisted multimodality data
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MIRAGE
integrin subunit alpha 2b
Summary
- Gene Symbol
-
- ITGA2B
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cell adhesion
- Cell membrane
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Integrin
- Metal-binding
- Proteomics identification
- Pyrrolidone carboxylic acid
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P08514 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis |
|
|
| positive regulation of leukocyte migration |
|
|
| cell adhesion |
|
|
| cell-matrix adhesion |
|
|
| cell-matrix adhesion |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
|
| focal adhesion |
|
|
| integrin complex |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell adhesion receptor activity |
|
|
| protein binding |
|
|
| signaling receptor activity |
|
|
| identical protein binding |
|
|
| metal ion binding |
|
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Integrin
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- P: Inorganic ion transport and metabolism
| Gene Ontology |
|---|
| angiogenesis |
| cell adhesion mediated by integrin |
| cell-matrix adhesion |
| integrin binding |
| integrin-mediated signaling pathway |
| InterPro |
|---|
| FG-GAP repeat |
| Integrin alpha beta-propellor |
| Integrin alpha, N-terminal |
| Integrin alpha, third immunoglobulin-like domain |
| Integrin domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1588 | thrombocytopenia | |
| DOID:2219 | Glanzmann's thrombasthenia | |
| DOID:0060573 | von Willebrand's disease 1 | |
| DOID:0060691 | platelet-type bleeding disorder 16 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 16399 | MGI:96601 | |
| 176240 | WB:WBGene00003929 | |
| 32661 | FB:FBgn0001250 |
