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Guidelines

MIRAGE

solute carrier family 26 member 5

Summary

Gene Symbol

SLC26A5

Organism

Homo sapiens (human)

External Links

NCBI Gene

375611

KEGG Gene ID

[""]

PubChem

375611

Alliance of Genome Resources

HGNC:9359

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell shape
Glycoprotein
Hearing
Motor protein
Non-syndromic deafness
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P58743	Solute carrier family 26 member 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 31 in total

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GO Term	Evidence Code	PMID
response to ischemia	IEA
chloride transport	ISS
chloride transport	IEA
sensory perception of sound	IMP
sensory perception of sound	IBA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

fructose transmembrane transport

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport

chloride transmembrane transport

sulfate transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

positive regulation of cell size

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure development [inference]

cochlea development

response to stimulus [inference]

response to stress [inference]

response to ischemia

response to external stimulus [inference]

response to mechanical stimulus [inference]

response to auditory stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

response to auditory stimulus

response to endogenous stimulus [inference]

response to hormone [inference]

response to thyroid hormone

response to chemical [inference]

response to xenobiotic stimulus

response to hormone [inference]

response to thyroid hormone

response to metal ion [inference]

response to potassium ion

response to oxygen-containing compound [inference]

response to salicylic acid

response to salt

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport

chloride transmembrane transport

monoatomic anion transmembrane transport

chloride transmembrane transport

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport

chloride transmembrane transport

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

fructose transmembrane transport

inorganic anion transport [inference]

chloride transport

chloride transmembrane transport

sulfate transmembrane transport

organic anion transport [inference]

bicarbonate transport

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

oxalate transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

oxalate transport

transmembrane transport

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

fructose transmembrane transport

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport

chloride transmembrane transport

sulfate transmembrane transport

sulfur compound transport [inference]

sulfate transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility

regulation of cell motility [inference]

positive regulation of cell motility

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility

positive regulation of cellular process [inference]

positive regulation of cell motility

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

positive regulation of cellular process [inference]

positive regulation of cell motility

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of cell motility [inference]

positive regulation of cell motility

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

positive regulation of cell size

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GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA
basolateral plasma membrane	ISS
basolateral plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

lateral plasma membrane

lateral part of cell [inference]

lateral wall of outer hair cell

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GO Term	Evidence Code	PMID
protein binding	IPI
secondary active sulfate transmembrane transporter activity	IEA
sulfate transmembrane transporter activity	IBA
oxalate transmembrane transporter activity	IBA
spectrin binding	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

bicarbonate transmembrane transporter activity [inference]

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

secondary active sulfate transmembrane transporter activity

antiporter activity [inference]

solute:inorganic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

oxalate transmembrane transporter activity

sulfur compound transmembrane transporter activity [inference]

sulfate transmembrane transporter activity

secondary active sulfate transmembrane transporter activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

spectrin binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

protein-containing complex binding [inference]

spectrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

SULFATE TRANSPORTER

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
bicarbonate transmembrane transporter activity
inorganic anion transmembrane transport
inorganic anion transport
monoatomic anion transmembrane transporter activity
oxalate transmembrane transporter activity
sulfate transmembrane transporter activity

Displaying **all 4** entries
InterPro
SLC26A/SulP transporter domain
SLC26A/SulP transporter
STAS domain superfamily
STAS domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110513	autosomal recessive nonsyndromic deafness 61	Alliance of Genome Resources

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026