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Sialyltransferase

Summary

Gene Symbol

SiaT

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

37950

KEGG Gene ID

PubChem

37950

Alliance of Genome Resources

FB:FBgn0035050

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9GU23
Q9W121

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
N-glycan processing	IDA
neuromuscular junction development	IMP
glycoprotein biosynthetic process	IEA
Golgi apparatus N-glycan diversification	IDA
Golgi apparatus N-glycan diversification	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

N-glycan processing

Golgi apparatus N-glycan diversification

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

N-glycan processing

Golgi apparatus N-glycan diversification

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

N-glycan processing

Golgi apparatus N-glycan diversification

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

N-glycan processing

Golgi apparatus N-glycan diversification

macromolecule modification [inference]

sialylation

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

N-glycan processing

Golgi apparatus N-glycan diversification

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

N-glycan processing

Golgi apparatus N-glycan diversification

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

N-glycan processing

Golgi apparatus N-glycan diversification

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization [inference]

neuromuscular junction development

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Golgi membrane	IDA
extracellular region	IDA
Golgi apparatus	IDA
Golgi apparatus	IBA
Golgi cisterna membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

organelle membrane [inference]

Golgi cisterna membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
beta-galactoside alpha-2,6-sialyltransferase activity	IDA
beta-galactoside alpha-2,6-sialyltransferase activity	IMP
beta-galactoside alpha-2,6-sialyltransferase activity	IBA
beta-galactoside alpha-2,6-sialyltransferase activity	IEA
sialyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity

beta-galactoside alpha-2,6-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
extracellular region	PMID:14612445
Golgi apparatus	PMID:14612445

Rhea

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H⁺ + CMP

Enzyme

2.4.3.1

PMID

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP

Enzyme

2.4.3.1

PMID

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP

Enzyme

2.4.3.1

PMID

2460092

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP008847
Gene Name: Sialyltransferase

Ortholog

Displaying entries **1 - 10** of 11 in total

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Species	Gene ID	Alliance of Genome Resources
Mus musculus	240119	MGI:2445190
Mus musculus	20440	MGI:108470
Rattus norvegicus	301155	RGD:1559663
Rattus norvegicus	25197	RGD:3676
Homo sapiens	6480	HGNC:10860
Homo sapiens	84620	HGNC:10861
Danio rerio	445376	ZFIN:ZDB-GENE-060322-3
Danio rerio	797439	ZFIN:ZDB-GENE-120426-2
Danio rerio	403116	ZFIN:ZDB-GENE-060322-4
Xenopus tropicalis	100491268	Xenbase:XB-GENE-983202

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Guidelines

Summary

External Links

Annotation

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements