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Guidelines

MIRAGE

B and T lymphocyte associated

Summary

Gene Symbol

Btla

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

407756

KEGG Gene ID

PubChem

407756

Alliance of Genome Resources

RGD:1303280

Annotation

Keyword

Adaptive immunity
Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6IQZ1
A0A1W2Q6H3
Q6PNM1	B- and T-lymphocyte-associated protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
adaptive immune response
immune response-regulating cell surface receptor signaling pathway	ISO
immune response-regulating cell surface receptor signaling pathway	IBA
immune response-regulating cell surface receptor signaling pathway	IEA
regulation of T cell tolerance induction to tumor cell	ISO

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway

response to stimulus [inference]

immune response [inference]

adaptive immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of tolerance induction [inference]

regulation of tolerance induction dependent upon immune response [inference]

regulation of peripheral tolerance induction [inference]

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of T cell tolerance induction [inference]

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of immune effector process [inference]

regulation of leukocyte mediated immunity [inference]

regulation of lymphocyte mediated immunity [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of tolerance induction dependent upon immune response [inference]

regulation of peripheral tolerance induction [inference]

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of T cell mediated immunity [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of immune response to tumor cell [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of response to tumor cell [inference]

regulation of immune response to tumor cell [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of tolerance induction dependent upon immune response [inference]

regulation of peripheral tolerance induction [inference]

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of T cell mediated immunity [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of immune response to tumor cell [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA
external side of plasma membrane	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
signaling receptor activity	ISO
signaling receptor activity	IBA
signaling receptor activity	IEA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	208154	MGI:2658978
Homo sapiens	151888	HGNC:21087

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Last updated: April 6, 2026