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Guidelines

MIRAGE

B and T lymphocyte associated

Summary

Gene Symbol

Btla

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

208154

KEGG Gene ID

PubChem

208154

Alliance of Genome Resources

MGI:2658978

Annotation

Keyword

3D-structure
Adaptive immunity
Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A0R4J1A0	B- and T-lymphocyte-associated protein
Q7TSA3	B- and T-lymphocyte-associated protein
E9QNY6	B- and T-lymphocyte-associated protein
Q32MV8	B- and T-lymphocyte-associated protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

1

2

3

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Last »
GO Term	Evidence Code	PMID
adaptive immune response
immune response-regulating cell surface receptor signaling pathway	IMP
immune response-regulating cell surface receptor signaling pathway	IBA
immune response-regulating cell surface receptor signaling pathway	IEA
regulation of T cell tolerance induction to tumor cell	ISO

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway

response to stimulus [inference]

immune response [inference]

adaptive immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of tolerance induction [inference]

regulation of tolerance induction dependent upon immune response [inference]

regulation of peripheral tolerance induction [inference]

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of T cell tolerance induction [inference]

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of immune effector process [inference]

regulation of leukocyte mediated immunity [inference]

regulation of lymphocyte mediated immunity [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of tolerance induction dependent upon immune response [inference]

regulation of peripheral tolerance induction [inference]

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of T cell mediated immunity [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of immune response to tumor cell [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of response to tumor cell [inference]

regulation of immune response to tumor cell [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of tolerance induction dependent upon immune response [inference]

regulation of peripheral tolerance induction [inference]

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of T cell mediated immunity [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of peripheral T cell tolerance induction [inference]

regulation of T cell tolerance induction to tumor cell

regulation of immune response to tumor cell [inference]

regulation of T cell mediated immune response to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of tolerance induction to tumor cell [inference]

regulation of T cell tolerance induction to tumor cell

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

Displaying entries **1 - 5** of 7 in total

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2

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GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI
signaling receptor activity	ISO
signaling receptor activity	IGI
signaling receptor activity	IBA
signaling receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	407756	RGD:1303280
Homo sapiens	151888	HGNC:21087

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Last updated: April 6, 2026