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surface glycoprotein

Summary

Gene Symbol

Organism

Severe acute respiratory syndrome coronavirus 2

External Links

NCBI Gene: 43740568
PubChem: 43740568

Annotation

Keyword

3D-structure
Coiled coil
Disulfide bond
Fusion of virus membrane with host endosomal membrane
Glycoprotein
Host cell membrane
Inhibition of host tetherin by virus
Palmitate
Reference proteome
Signal
Superantigen
Transmembrane helix
Viral attachment to host cell
Viral envelope protein
Virulence

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P0DTC2	E2 Peplomer protein
A0A6G7K2L4	E2 Peplomer protein
A0A679G9E9	E2 Peplomer protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
virion attachment to host cell
fusion of virus membrane with host plasma membrane
viral translation
suppression by virus of host tetherin activity
fusion of virus membrane with host endosome membrane

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

endocytosis involved in viral entry into host cell

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

membrane fusion

fusion of virus membrane with host plasma membrane

viral process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

viral translation

membrane fusion involved in viral entry into host cell [inference]

transport of virus [inference]

endocytosis involved in viral entry into host cell

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

adhesion of symbiont to host [inference]

adhesion of symbiont to host cell [inference]

virion attachment to host cell

receptor-mediated virion attachment to host cell

entry receptor-mediated virion attachment to host cell

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

suppression by virus of host tetherin activity

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

endocytosis involved in viral entry into host cell

import into cell [inference]

endocytosis [inference]

endocytosis involved in viral entry into host cell

biological regulation [inference]

regulation of biological process [inference]

regulation of biological process involved in symbiotic interaction [inference]

modulation by symbiont of entry into host [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

positive regulation of biological process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

regulation of viral process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

regulation of viral life cycle [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
plasma membrane
membrane
viral envelope
host cell plasma membrane
host extracellular space

GO Hierarchy

cellular component

virion component [inference]

viral membrane [inference]

viral envelope

virion membrane

cellular anatomical entity [inference]

membrane

plasma membrane

host cellular component [inference]

host cell part [inference]

host cell membrane [inference]

host cell surface

host extracellular space

Displaying **all 4** entries
GO Term	Evidence Code	PMID
structural constituent of virion
identical protein binding
host cell surface receptor binding
receptor ligand activity

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of virion

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor ligand activity

identical protein binding

host cell surface binding [inference]

host cell surface receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements