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G protein-coupled receptor 143
Summary
- Gene Symbol
-
- GPR143
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Albinism
- Cell membrane
- Disease variant
- G-protein coupled receptor
- Glycoprotein
- Lysosome
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P51810 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| eye pigment biosynthetic process |
|
|
| signal transduction |
|
|
| G protein-coupled receptor signaling pathway |
|
|
| G protein-coupled receptor signaling pathway |
|
|
| G protein-coupled receptor signaling pathway |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleoplasm |
|
|
| cytoplasm |
|
|
| lysosomal membrane |
|
|
| lysosomal membrane |
|
|
| lysosomal membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor activity |
|
|
| G protein-coupled receptor activity |
|
|
| G protein-coupled receptor activity |
|
|
| protein binding |
|
|
| dopamine binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- G-protein coupled receptor 143
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| L-DOPA binding |
| L-DOPA receptor activity |
| dopamine binding |
| melanosome organization |
| regulation of calcium-mediated signaling |
| tyrosine binding |
| InterPro |
|---|
| G-protein coupled receptor 143 |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050633 | ocular albinism 1 | |
| DOID:0111795 | congenital nystagmus 6 |
