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MIRAGE
G-protein coupled receptor 143
Summary
- UniProt ID
- P51810
- Gene Symbol
-
- GPR143
- OA1
- Gene ID
- 4935
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Albinism
- Cell membrane
- Disease variant
- G-protein coupled receptor
- Glycoprotein
- Lysosome
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| membrane |
| melanosome |
| Golgi apparatus |
| apical plasma membrane |
| lysosomal membrane |
| melanosome membrane |
| GO Term |
|---|
| dopamine binding |
| tyrosine binding |
| L-DOPA receptor activity |
| L-DOPA binding |
| G protein-coupled receptor activity |
Sequence
MASPRLGTFCCPTRDAATQLVLSFQPRAFHALCLGSGGLRLALGLLQLLPGRRPAGPGSPATSPPASVRILRAAAACDLLGCLGMVIRSTVWLGFPNFVDSVSDMNHTEIWPAAFCVGSAMWIQLLYSACFWWLFCYAVDAYLVIRRSAGLSTILLYHIMAWGLATLLCVEGAAMLYYPSVSRCERGLDHAIPHYVTMYLPLLLVLVANPILFQKTVTAVASLLKGRQGIYTENERRMGAVIKIRFFKIMLVLIICWLSNIINESLLFYLEMQTDINGGSLKPVRTAAKTTWFIMGILNPAQGFLLSLAFYGWTGCSLGFQSPRKEIQWESLTTSAAEGAHPSPLMPHENPASGKVSQVGGQTSDEALSMLSEGSDASTIEIHTASESCNKNEGDPALPTHGDL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 106 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Amine ligand-binding receptors | Homo sapiens |
| G alpha (q) signalling events | Homo sapiens |
| Regulation of MITF-M-dependent genes involved in pigmentation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050633 | ocular albinism 1 | |
| DOID:0111795 | congenital nystagmus 6 |
