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Amine ligand-binding receptors

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-375280

PubChem

R-HSA-375280

Description

The class A (rhodopsin-like) GPCRs that bind to classical biogenic amine ligands are annotated here. The amines involved (acetylcholine, adrenaline, noradrenaline, dopamine, serotonin and histamine) can all act as neurotransmitters in humans. The so-called 'trace amines', used when referring to p-tyramine, beta-phenylethylamine, tryptamine and octopamine, can also bind to recently-discovered GPCRs.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 8** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O14804	Trace amine-associated receptor 5	PNR TAAR5	view
P51810	G-protein coupled receptor 143	GPR143 OA1	view
Q969N4	Trace amine-associated receptor 8	GPR102 TA5 TAAR8 TAR5 TRAR5	view
Q96RI8	Trace amine-associated receptor 6	TA4 TAAR6 TAR4 TRAR4	view
Q96RI9	Trace amine-associated receptor 9	TA3 TAAR9 TAR3 TRAR3	view
Q96RJ0	Trace amine-associated receptor 1	TA1 TAAR1 TAR1 TRAR1	view
Q9P1P4	Putative trace amine-associated receptor 3	GPR57 TAAR3 TAAR3P	view
Q9P1P5	Trace amine-associated receptor 2	GPR58 TAAR2	view

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