GlyCosmos Portal

Submissions

angiotensin I converting enzyme (peptidyl-dipeptidase A) 3

Summary

Gene Symbol

Ace3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

498012

KEGG Gene ID

PubChem

498012

Alliance of Genome Resources

RGD:1561299

Annotation

Keyword

Carboxypeptidase
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Signal
Transmembrane helix
Zinc

Proteins

Displaying **all 3** entries
UniProt	Protein Name
M0RB66
A6HJZ6
A0ABK0LK40

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
angiotensin maturation	IBA
positive regulation of systemic arterial blood pressure	IBA
positive regulation of systemic arterial blood pressure	IEA
proteolysis	IEA
male gonad development	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

anatomical structure development [inference]

animal organ development [inference]

gonad development [inference]

male gonad development

reproductive structure development [inference]

gonad development [inference]

male gonad development

biological regulation [inference]

regulation of biological process [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation

regulation of biological quality [inference]

regulation of blood pressure [inference]

positive regulation of blood pressure [inference]

positive regulation of systemic arterial blood pressure

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
acrosomal vesicle	IEA
extracellular region	IBA
obsolete extracellular space
plasma membrane	IBA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
carboxypeptidase activity
metallopeptidase activity	IBA
metallopeptidase activity	IEA
peptidyl-dipeptidase activity	IBA
peptidyl-dipeptidase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

angiotensin-converting enzyme

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
carboxypeptidase activity
hydrolase activity
metal ion binding
metallopeptidase activity
peptidyl-dipeptidase activity
positive regulation of systemic arterial blood pressure
proteolysis
regulation of systemic arterial blood pressure by renin-angiotensin

Displaying 1 entry
InterPro
Peptidase M2, peptidyl-dipeptidase A

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	217246	MGI:3644400
Caenorhabditis elegans	180780	WB:WBGene00000039
Drosophila melanogaster	34805	FB:FBgn0012037
Drosophila melanogaster	34808	FB:FBgn0032536
Drosophila melanogaster	34189	FB:FBgn0016122
Danio rerio	565980	ZFIN:ZDB-GENE-030131-1826