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regulator of G-protein signaling 6

Summary

Gene Symbol

Rgs6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

50779

KEGG Gene ID

PubChem

50779

Alliance of Genome Resources

MGI:1354730

Annotation

Keyword

Cell membrane
Cytoplasm
Nucleus
Proteomics identification
Reference proteome
Signal transduction inhibitor

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q3UTM5
A0A087WNZ9
Q9Z2H2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	TAS
G protein-coupled receptor signaling pathway	IBA
G protein-coupled receptor signaling pathway	IEA
regulation of G protein-coupled receptor signaling pathway	IEA
negative regulation of signal transduction

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of response to stimulus [inference]

negative regulation of signal transduction

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of cellular process [inference]

signal transduction [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

positive regulation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	ISO
nucleus	IEA
nucleoplasm	ISO
cytoplasm	ISO

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

membrane

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

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GO Term	Evidence Code	PMID
GTPase activator activity	ISS
GTPase activator activity	ISO
GTPase activator activity	TAS
GTPase activator activity	IBA
GTPase activator activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

protein domain specific binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

G-protein signaling regulator

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
regulation of G protein-coupled receptor signaling pathway

Displaying entries **1 - 10** of 11 in total

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InterPro
DEP domain
G-protein gamma-like domain superfamily
G-protein gamma-like domain
RGS domain superfamily
RGS domain
RGS, subdomain 2
Regulator of G protein signaling 6/7/9/11
Regulator of G-protein signalling 6/7/9/11, DHEX domain superfamily
Regulator of G-protein signalling, DHEX domain
Winged helix DNA-binding domain superfamily