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Regulator of G-protein signaling 6

Summary

UniProt ID: Q9Z2H2
Gene Symbol: Rgs6
Gene ID: 50779
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q9Z2H2
PubChem: Q9Z2H2
The O-GlcNAc Database: Q9Z2H2
O-GlcNAcAtlas: Q9Z2H2
Re-Glyco: Q9Z2H2

Annotation

Keyword: Cell membrane Cytoplasm Nucleus Reference proteome Signal transduction inhibitor

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
G protein-coupled receptor signaling pathway	TAS	PMID
G protein-coupled receptor signaling pathway	IBA	GO_REF
G protein-coupled receptor signaling pathway	IEA	GO_REF
regulation of G protein-coupled receptor signaling pathway	IEA	GO_REF GO_REF
negative regulation of signal transduction

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of response to stimulus [inference]

negative regulation of signal transduction

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of cellular process [inference]

signal transduction [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

positive regulation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

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GO Term	Evidence Code	Reference
nucleus	ISS	GO_REF
nucleus	ISO	GO_REF
nucleus	IEA	GO_REF
cytoplasm	ISO	GO_REF
cytoplasm	EXP	PMID

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

membrane

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

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GO Term	Evidence Code	Reference
GTPase activator activity	ISS	GO_REF
GTPase activator activity	ISO	GO_REF
GTPase activator activity	TAS	PMID
GTPase activator activity	IBA	GO_REF
GTPase activator activity	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

protein domain specific binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites