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phospholipid phosphatase 2

Summary

Gene Symbol

Plpp2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

50784

KEGG Gene ID

PubChem

50784

Alliance of Genome Resources

MGI:1354945

Annotation

Keyword

Alternative splicing
Cell membrane
Endoplasmic reticulum
Endosome
Glycoprotein
Hydrolase
Lipid metabolism
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q9DAX2	Lipid phosphate phosphohydrolase 2 PAP2-gamma Phosphatidate phosphohydrolase type 2c Phosphatidic acid phosphatase 2c
G3XA61
A0A1W2P7I9

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
phospholipid metabolic process	ISS
phospholipid metabolic process	ISO
phospholipid metabolic process	IBA
phospholipid metabolic process	IEA
sphingosine metabolic process	ISS

GO Hierarchy

biological process

cellular process [inference]

signal transduction

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

dephosphorylation [inference]

phospholipid dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

lipid modification [inference]

phospholipid dephosphorylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cell cycle phase transition [inference]

regulation of cell cycle G1/S phase transition

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
early endosome	ISS
early endosome	ISO
early endosome	IEA
endoplasmic reticulum	ISS
endoplasmic reticulum	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

early endosome membrane

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
phosphatidate phosphatase activity	ISS
phosphatidate phosphatase activity	ISO
phosphatidate phosphatase activity	IBA
phosphatidate phosphatase activity	IEA
sphingosine-1-phosphate phosphatase activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

lipid phosphatase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphatidate phosphatase

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
phospholipid dephosphorylation
phospholipid metabolic process

Displaying **all 3** entries
InterPro
Phosphatidate (PA) phosphatase-related
Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
Phosphatidic acid phosphatase type 2/haloperoxidase