GlyCosmos Portal

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GO Term	Evidence Code	PMID
iron ion binding	IEA
procollagen-lysine 5-dioxygenase activity	ISS	9582318
procollagen-lysine 5-dioxygenase activity	IDA	10934207
procollagen-lysine 5-dioxygenase activity	IBA
L-ascorbic acid binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

dioxygenase activity [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

glucosyltransferase activity [inference]

procollagen glucosyltransferase activity

catalytic activity, acting on a protein [inference]

procollagen glucosyltransferase activity

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

L-ascorbic acid binding

small molecule binding [inference]

vitamin binding [inference]

L-ascorbic acid binding

organic acid binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

monosaccharide binding [inference]

L-ascorbic acid binding

heterocyclic compound binding [inference]

L-ascorbic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

L-ascorbic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Procollagen-lysine,2-oxoglutarate 5-dioxygenase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
L-ascorbic acid binding
dioxygenase activity
iron ion binding
metal ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity
procollagen-proline 4-dioxygenase activity

Displaying **all 4** entries
InterPro
Oxoglutarate/iron-dependent dioxygenase
Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain
Prolyl 4-hydroxylase, alpha subunit
Prolyl 4-hydroxylase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060231	Bruck syndrome	Glyco-Disease Genes Database

Ortholog

Displaying entries **41 - 50** of 83 in total

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Species	Gene ID	Orthologous MAtrix
Mustela putorius furo	101690556	MUSPF12621
Ficedula albicollis	101811005	FICAL01458
Macaca fascicularis	101866274	MACFA26228
Melopsittacus undulatus	101881030	MELUD10393
Chrysemys picta bellii	101949154	CHRPI16008
Ictidomys tridecemlineatus	101966027	ICTTR10775
Capra hircus	102176366	CAPHI12499
Latimeria chalumnae	102364901	LATCH09345
Pelodiscus sinensis	102445695	PELSI06236
Callorhinchus milii	103177516	CALMI00297

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Acknowledgements