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MIRAGE
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Summary
- Gene Symbol
-
- PLOD2
- Aliases
-
- LH2
- TLH
- lysyl hydroxlase 2
- procollagen lysyl hydroxylase 2
- telopeptidyl lysyl hydroxylase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Dioxygenase
- Disease variant
- Endoplasmic reticulum
- Glycoprotein
- Iron
- Membrane
- Metal-binding
- Osteogenesis imperfecta
- Phosphoprotein
- Reference proteome
- Signal
- Vitamin C
- Proteins
| UniProt | Protein Name |
|---|---|
| O00469 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein modification process | ||
| hydroxylysine biosynthetic process |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane | ||
| Golgi apparatus | ||
| rough endoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| iron ion binding | ||
| procollagen-lysine 5-dioxygenase activity | ||
| procollagen-lysine 5-dioxygenase activity | ||
| procollagen-lysine 5-dioxygenase activity | ||
| L-ascorbic acid binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Procollagen-lysine,2-oxoglutarate 5-dioxygenase
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060231 | Bruck syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 106823925 | EQUAS00083 | ||
| 107588036 | SINGR07607 | ||
| 108272656 | ICTPU14701 | ||
| 108540316 | RHIBE35378 | ||
| 109099667 | CYPCA121250 | ||
| 109308580 | CROPO15452 | ||
| 110204809 | PHACI15346 | ||
| 113436878 | PSETE07911 | ||
| 113582141 | ELEEL27695 | ||
| 113894127 | BOBOX28932 |
