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core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

Summary

Gene Symbol

C1GALT1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 539417
KEGG Gene ID: bta:539417
PubChem: 539417

Annotation

Keyword

Angiogenesis
Developmental protein
Differentiation
Disulfide bond
Glycosyltransferase
Manganese
Metal-binding
Nucleotide-binding
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q0VC84	Core 1 O-glycan T-synthase Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 Core 1 beta1,3-galactosyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
angiogenesis
kidney development
protein glycosylation
O-glycan processing, core 1	IEA	30032202
cell differentiation

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 1

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 1

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 1

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 1

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 1

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 1

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 1

cellular process [inference]

cellular developmental process [inference]

cell differentiation

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

animal organ development [inference]

kidney development

cellular developmental process [inference]

cell differentiation

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleotide binding
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	IEA	30032202
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

galactosyltransferase activity [inference]

beta-1,3-galactosyltransferase activity [inference]

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

Displaying **all 2** entries
InterPro
C1GALT1/C1GALT1-specific chaperone 1
Fringe-like, glycosyltransferase domain

KEGG BRITE Database

Orthology

K00731

Name

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122]

References

11677243

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05908	2.4.1.122	G57321FI	G00031MO

Rhea

RHEA:15621

an N-acetyl-α-D-galactosaminyl derivative + UDP-α-D-galactose

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + H⁺ + UDP

Enzyme

2.4.1.122

PMID

Ortholog

Displaying entries **31 - 40** of 72 in total

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Species	Gene ID	Orthologous MAtrix
Heterocephalus glaber	101704643	HETGA26615
Anas platyrhynchos platyrhynchos	101797632	ANAPP07762
Ficedula albicollis	101810221	FICAL00754
Melopsittacus undulatus	101879719	MELUD01679
Chrysemys picta bellii	101942937	CHRPI08363
Ictidomys tridecemlineatus	101971623	ICTTR01474
Chinchilla lanigera	102025281	CHILA09057
Macaca fascicularis	102137839	MACFA29811
Capra hircus	102169248	CAPHI24020
Latimeria chalumnae	102345499	LATCH11102

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Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements