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Submissions

ectonucleotide pyrophosphatase/phosphodiesterase 3

Summary

Gene Symbol

Enpp3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

54410

PubChem

54410

Alliance of Genome Resources

RGD:708511

Annotation

Keyword

3D-structure
ATP-binding
Calcium
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Hydrolase
Metal-binding
Reference proteome
Repeat
Secreted
Signal-anchor
Transmembrane helix
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6JUK4	Phosphodiesterase I beta Phosphodiesterase I/nucleotide pyrophosphatase 3
P97675	Alkaline phosphodiesterase I B10 Dinucleoside polyphosphatase Nucleotide diphosphatase Nucleotide pyrophosphatase Phosphodiesterase I beta Phosphodiesterase I/nucleotide pyrophosphatase 3 RB13-6 antigen

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **16 - 20** of 24 in total

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GO Term	Evidence Code	PMID
negative regulation of inflammatory response	ISS
negative regulation of inflammatory response	ISO
negative regulation of inflammatory response	IEA
regulation of smooth muscle cell differentiation	NAS	9642040
phosphate ion homeostasis	ISO

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

basophil activation involved in immune response

leukocyte activation [inference]

myeloid leukocyte activation [inference]

granulocyte activation [inference]

basophil activation [inference]

basophil activation involved in immune response

leukocyte activation involved in immune response [inference]

basophil activation involved in immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleotide metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleotide metabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic substance catabolic process [inference]

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleotide metabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleotide metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleotide metabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleotide metabolic process

organic substance catabolic process [inference]

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

basophil activation involved in immune response

leukocyte activation [inference]

myeloid leukocyte activation [inference]

granulocyte activation [inference]

basophil activation [inference]

basophil activation involved in immune response

leukocyte activation involved in immune response [inference]

basophil activation involved in immune response

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleotide metabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine nucleotide metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribonucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleotide metabolic process

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

basophil activation involved in immune response

leukocyte activation [inference]

myeloid leukocyte activation [inference]

granulocyte activation [inference]

basophil activation [inference]

basophil activation involved in immune response

leukocyte activation involved in immune response [inference]

basophil activation involved in immune response

homeostatic process [inference]

chemical homeostasis [inference]

inorganic ion homeostasis [inference]

phosphate ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

inorganic anion transport [inference]

inorganic diphosphate transport

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of immune effector process [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of immune response [inference]

negative regulation of mast cell activation involved in immune response

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

regulation of mast cell activation involved in immune response [inference]

negative regulation of mast cell activation involved in immune response

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

regulation of mast cell activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

regulation of mast cell activation involved in immune response [inference]

negative regulation of mast cell activation involved in immune response

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of mast cell activation involved in immune response

positive regulation of immune effector process [inference]

regulation of mast cell activation involved in immune response [inference]

negative regulation of mast cell activation involved in immune response

regulation of immune response [inference]

regulation of mast cell activation involved in immune response [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of immune response [inference]

negative regulation of mast cell activation involved in immune response

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

regulation of mast cell activation involved in immune response [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of immune effector process [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of immune response [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mast cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

negative regulation of immune response [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

negative regulation of immune response [inference]

negative regulation of mast cell activation involved in immune response

regulation of immune response [inference]

regulation of mast cell activation involved in immune response [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of immune response [inference]

negative regulation of mast cell activation involved in immune response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of muscle cell differentiation [inference]

regulation of smooth muscle cell differentiation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mast cell proliferation

regulation of leukocyte proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mast cell proliferation

regulation of mast cell proliferation [inference]

negative regulation of mast cell proliferation

regulation of cell differentiation [inference]

regulation of muscle cell differentiation [inference]

regulation of smooth muscle cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mast cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

regulation of mast cell activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

regulation of mast cell activation involved in immune response [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

regulation of mast cell activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

regulation of mast cell activation involved in immune response [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of mast cell activation [inference]

negative regulation of mast cell activation involved in immune response

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
plasma membrane	ISS
plasma membrane	ISO
external side of plasma membrane	ISS
external side of plasma membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

perinuclear region of cytoplasm

side of membrane [inference]

external side of plasma membrane

Displaying entries **6 - 10** of 25 in total

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GO Term	Evidence Code	PMID
phosphodiesterase I activity	TAS	9096610
dinucleotide phosphatase activity	TAS	9096610
calcium ion binding	ISS
calcium ion binding	ISO
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

exonuclease activity [inference]

phosphodiesterase I activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

phosphodiesterase I activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

dinucleotide phosphatase activity

bis(5'-nucleosyl)-tetraphosphatase activity [inference]

bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity

bis(5'-adenosyl)-pentaphosphatase activity

nucleoside triphosphate diphosphatase activity

bis(5'-adenosyl)-triphosphatase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Ectonucleotide pyrophosphatase/phosphodiesterase

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
nucleoside triphosphate diphosphatase activity

Displaying **all 2** entries
InterPro
Alkaline-phosphatase-like, core domain superfamily
Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase

Rhea

RHEA:29391

H₂O + GTP

H⁺ + diphosphate + GMP

Enzyme

PMID

12218018

RHEA:10248

H₂O + dUTP

H⁺ + dUMP + diphosphate

Enzyme

PMID

RHEA:14245

H₂O + ATP

H⁺ + diphosphate + AMP

Enzyme

PMID

12218018

RHEA:23996

H₂O + a ribonucleoside 5'-triphosphate

H⁺ + diphosphate + a ribonucleoside 5'-phosphate

Enzyme

3.6.1.9

PMID

12218018

RHEA:27762

H₂O + CTP

H⁺ + diphosphate + CMP

Enzyme

PMID

RHEA:28362

H₂O + dGTP

H⁺ + diphosphate + dGMP

Enzyme

3.6.1.9

PMID

RHEA:28534

H₂O + dTTP

H⁺ + diphosphate + dTMP

Enzyme

3.6.1.9

PMID

RHEA:22636

H₂O + dCTP

H⁺ + diphosphate + dCMP

Enzyme

PMID

RHEA:28334

H₂O + dATP

H⁺ + diphosphate + dAMP

Enzyme

3.6.1.9

PMID

RHEA:44644

H₂O + a 2'-deoxyribonucleoside 5'-triphosphate

H⁺ + diphosphate + a 2'-deoxyribonucleoside 5'-phosphate

Enzyme

3.6.1.9

PMID

12218018

RHEA:29395

H₂O + UTP

H⁺ + diphosphate + UMP

Enzyme

PMID

RHEA:28610

H₂O + XTP

H⁺ + diphosphate + XMP

Enzyme

PMID

RHEA:28342

H₂O + dITP

H⁺ + diphosphate + dIMP

Enzyme

PMID

RHEA:29399

H₂O + ITP

H⁺ + diphosphate + IMP

Enzyme

PMID

Ortholog

Displaying entries **81 - 86** of 86 in total

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Species	Gene ID	Orthologous MAtrix
Podarcis muralis	114594147	PODMU17805
Corvus moneduloides	116440693	CORMO19096
Rhinolophus ferrumequinum	117020880	RHIFE10690
Balaenoptera musculus	118904949	BALMU27139
Panthera leo	122219170	PANLE16411
Ursus americanus	123797586	URSAM09280

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements