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solute carrier family 22 (organic cation transporter), member 21

Summary

Gene Symbol

Slc22a21

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56517

KEGG Gene ID

PubChem

56517

Alliance of Genome Resources

MGI:1929481

Annotation

Keyword

ATP-binding
Glycoprotein
Ion transport
Peroxisome
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A2RSK7
Q9WTN6	Organic cation/carnitine transporter 3 Solute carrier family 22 member 9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
response to symbiotic bacterium	ISO
quaternary ammonium group transport	ISO
quaternary ammonium group transport	IBA
carnitine transport	ISO
carnitine transport	IDA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

carnitine transmembrane transport

(R)-carnitine transmembrane transport

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to symbiont [inference]

response to symbiotic bacterium

response to bacterium [inference]

response to symbiotic bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to symbiont [inference]

response to symbiotic bacterium

response to bacterium [inference]

response to symbiotic bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to symbiont [inference]

response to symbiotic bacterium

response to bacterium [inference]

response to symbiotic bacterium

response to chemical [inference]

response to peptide [inference]

response to cytokine [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

organic cation transport [inference]

carnitine transport

(R)-carnitine transport

(R)-carnitine transmembrane transport

carnitine transmembrane transport

(R)-carnitine transmembrane transport

sodium-dependent organic cation transport

transmembrane transport

carnitine transmembrane transport

(R)-carnitine transmembrane transport

nitrogen compound transport [inference]

quaternary ammonium group transport

amino-acid betaine transport [inference]

carnitine transport

(R)-carnitine transport

(R)-carnitine transmembrane transport

carnitine transmembrane transport

(R)-carnitine transmembrane transport

modified amino acid transport [inference]

amino-acid betaine transport [inference]

carnitine transport

(R)-carnitine transport

(R)-carnitine transmembrane transport

carnitine transmembrane transport

(R)-carnitine transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal epithelial structure maintenance

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of digestive system process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal epithelial structure maintenance

regulation of intestinal epithelial structure maintenance [inference]

positive regulation of intestinal epithelial structure maintenance

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal epithelial structure maintenance

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
peroxisome	IDA
peroxisomal membrane	IDA
peroxisomal membrane	IEA
endoplasmic reticulum	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

plasma membrane region [inference]

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

microbody [inference]

peroxisome

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
ATP binding
amino-acid betaine transmembrane transporter activity	ISO
carnitine transmembrane transporter activity	ISO
carnitine transmembrane transporter activity	IDA
carnitine transmembrane transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

quaternary ammonium group transmembrane transporter activity

amino-acid betaine transmembrane transporter activity

carnitine transmembrane transporter activity

(R)-carnitine transmembrane transporter activity

modified amino acid transmembrane transporter activity [inference]

amino-acid betaine transmembrane transporter activity

carnitine transmembrane transporter activity

(R)-carnitine transmembrane transporter activity

binding [inference]

protein binding [inference]

protein domain specific binding [inference]

PDZ domain binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Solute carrier family 22 member 22

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator, sugar transporter-like

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	29726	RGD:3702
Caenorhabditis elegans	172841	WB:WBGene00003842
Drosophila melanogaster	42890	FB:FBgn0086365
Drosophila melanogaster	42891	FB:FBgn0019952
Homo sapiens	6584	HGNC:10969
Saccharomyces cerevisiae S288C	850462	SGD:S000000695