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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

serglycin

Summary

Gene Symbol

Srgn

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

56782

PubChem

56782

Alliance of Genome Resources

RGD:619969

Annotation

Keyword

Apoptosis
Biomineralization
Direct protein sequencing
Disulfide bond
Golgi apparatus
Lysosome
Proteoglycan
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P04917	Chondroitin sulfate proteoglycan core protein Cytolytic granule proteoglycan core protein PG19 core protein Proteoglycan 10K core protein Secretory granule proteoglycan core protein
A6K451

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
negative regulation of cytokine production	ISS
negative regulation of cytokine production	ISO
apoptotic process	IEA
biological_process	ND
protein processing	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

cellular process [inference]

signal transduction [inference]

granzyme-mediated programmed cell death signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein location in mast cell secretory granule [inference]

maintenance of protease location in mast cell secretory granule

maintenance of protein location in T cell secretory granule [inference]

maintenance of protease location in T cell secretory granule [inference]

maintenance of granzyme B location in T cell secretory granule

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

secretory granule organization

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

biomineral tissue development

localization [inference]

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

maintenance of protein location in mast cell secretory granule [inference]

maintenance of protease location in mast cell secretory granule

maintenance of protein location in T cell secretory granule [inference]

maintenance of protease location in T cell secretory granule [inference]

maintenance of granzyme B location in T cell secretory granule

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein location in mast cell secretory granule [inference]

maintenance of protease location in mast cell secretory granule

maintenance of protein location in T cell secretory granule [inference]

maintenance of protease location in T cell secretory granule [inference]

maintenance of granzyme B location in T cell secretory granule

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of developmental process [inference]

negative regulation of biomineral tissue development [inference]

negative regulation of bone mineralization

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production

negative regulation of ossification [inference]

negative regulation of bone mineralization

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of biomineral tissue development [inference]

negative regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

negative regulation of bone mineralization

negative regulation of biomineral tissue development [inference]

negative regulation of bone mineralization

regulation of cellular process [inference]

signal transduction [inference]

granzyme-mediated programmed cell death signaling pathway

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

regulation of ossification [inference]

negative regulation of ossification [inference]

negative regulation of bone mineralization

regulation of bone mineralization [inference]

negative regulation of bone mineralization

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production

negative regulation of ossification [inference]

negative regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

negative regulation of bone mineralization

negative regulation of biomineral tissue development [inference]

negative regulation of bone mineralization

Displaying entries **1 - 5** of 10 in total

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2

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GO Term	Evidence Code	PMID
Golgi membrane	IDA	12602945
extracellular space	ISS
extracellular space	ISO
Golgi apparatus	ISS
Golgi apparatus	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

zymogen granule

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

zymogen granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

zymogen granule

Displaying 1 entry
GO Term	Evidence Code	PMID
collagen binding	IDA	9207929

GO Hierarchy

molecular function

binding [inference]

protein-containing complex binding [inference]

collagen binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
Golgi membrane	PMID:12602945
zymogen granule	PMID:12602945

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Last updated: April 6, 2026