GlyCosmos Portal

Submissions

prostaglandin E receptor 3

Summary

Gene Symbol

PTGER3

Organism

Homo sapiens (human)

External Links

NCBI Gene

5733

PubChem

5733

Alliance of Genome Resources

HGNC:9595

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
G-protein coupled receptor
Glycoprotein
Palmitate
Proteomics identification
Receptor
Reference proteome
Transducer
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P43115	PGE2-R Prostanoid EP3 receptor
O00325	Prostanoid EP3 receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
inflammatory response	IBA
G protein-coupled receptor signaling pathway	TAS	8307176
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA
phospholipase C-activating G protein-coupled receptor signaling pathway	IBA
positive regulation of cytosolic calcium ion concentration	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

cell death

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction [inference]

phasic smooth muscle contraction [inference]

intestine smooth muscle contraction

gastro-intestinal system smooth muscle contraction [inference]

intestine smooth muscle contraction

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of gastric acid secretion

regulation of gastric acid secretion [inference]

negative regulation of gastric acid secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of gastric acid secretion

positive regulation of biological process [inference]

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

positive regulation of multicellular organismal process [inference]

positive regulation of heat generation [inference]

positive regulation of fever generation

negative regulation of biological process [inference]

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of gastric acid secretion

negative regulation of multicellular organismal process [inference]

negative regulation of digestive system process [inference]

negative regulation of gastric acid secretion

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of fever generation [inference]

positive regulation of fever generation

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of fever generation [inference]

positive regulation of fever generation

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response [inference]

positive regulation of fever generation

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of heat generation [inference]

regulation of fever generation [inference]

positive regulation of fever generation

positive regulation of heat generation [inference]

positive regulation of fever generation

regulation of system process [inference]

regulation of digestive system process [inference]

regulation of gastric acid secretion [inference]

negative regulation of gastric acid secretion

negative regulation of digestive system process [inference]

negative regulation of gastric acid secretion

positive regulation of multicellular organismal process [inference]

positive regulation of heat generation [inference]

positive regulation of fever generation

negative regulation of multicellular organismal process [inference]

negative regulation of digestive system process [inference]

negative regulation of gastric acid secretion

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nuclear envelope	TAS	10336471
plasma membrane	TAS
plasma membrane	IDA	31097585
plasma membrane	IBA
membrane	NAS	9073510

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

Displaying **all 3** entries
GO Term	Evidence Code	PMID
prostaglandin E receptor activity	NAS	9073510
prostaglandin E receptor activity	IBA
protein binding	IPI	25416956

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

prostaglandin receptor activity [inference]

prostaglandin E receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

prostaglandin e2 receptor ep3 subtype

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
inflammatory response
positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Prostanoid receptor

Ortholog

Displaying entries **91 - 98** of 98 in total

« First

‹ Prev

…

6

7

8

9

10
Species	Gene ID	Orthologous MAtrix
Taeniopygia guttata	115496179	TAEGU29608
Gadus morhua	115556248	GADMO06733
Sparus aurata	115591863	SPAAU69866
Strigops habroptila	115611486	STRHB12416
Chelonoidis abingdonii	116824527	CHEAB22363
Scophthalmus maximus	118318267	SCOMX04079
Balaenoptera musculus	118905534	BALMU23219
Panthera leo	122227564	PANLE10302