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Rh associated glycoprotein

Summary

Gene Symbol

RHAG

Organism

Homo sapiens (human)

External Links

NCBI Gene

6005

KEGG Gene ID

PubChem

6005

Alliance of Genome Resources

HGNC:10006

Annotation

Keyword

3D-structure
Alternative splicing
Ammonia transport
Direct protein sequencing
Disease variant
Glycoprotein
Hereditary hemolytic anemia
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q96E98	Erythrocyte membrane glycoprotein Rh50 Rhesus blood group family type A glycoprotein
Q02094	Erythrocyte membrane glycoprotein Rh50 Erythrocyte plasma membrane 50 kDa glycoprotein Rhesus blood group family type A glycoprotein Rhesus blood group-associated ammonia channel Rhesus blood group-associated glycoprotein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
intracellular monoatomic ion homeostasis	IDA
carbon dioxide transport	IDA
bicarbonate transport	TAS
carbon dioxide transmembrane transport	IDA
erythrocyte development

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

transmembrane transport

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

cellular developmental process [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis

monoatomic cation homeostasis [inference]

multicellular organismal-level iron ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis

inorganic ion homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

gas transport [inference]

carbon dioxide transport

carbon dioxide transmembrane transport

organic cation transport [inference]

methylammonium transport [inference]

methylammonium transmembrane transport

organic anion transport [inference]

bicarbonate transport

one-carbon compound transport [inference]

carbon dioxide transport

carbon dioxide transmembrane transport

methylammonium transport [inference]

methylammonium transmembrane transport

transmembrane transport

nitrogen compound transport [inference]

amine transport [inference]

methylammonium transport [inference]

methylammonium transmembrane transport

ammonium transmembrane transport

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
plasma membrane	IEA
membrane	EXP

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

ankyrin-1 complex

cellular anatomical structure [inference]

membrane

plasma membrane

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
ammonium channel activity	TAS
ammonium channel activity	IDA
ammonium channel activity	IGI
ammonium channel activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

amine transmembrane transporter activity [inference]

methylammonium transmembrane transporter activity

passive transmembrane transporter activity [inference]

channel activity [inference]

ammonium channel activity

narrow pore channel activity [inference]

leak channel activity

carbon dioxide transmembrane transporter activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

ankyrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Ammonium transporter Rh type

Functional Category

E: Amino acid transport and metabolism
K: Transcription
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
ammonium homeostasis

Displaying **all 3** entries
InterPro
Ammonium transporter AmtB-like domain
Ammonium/urea transporter
Blood group Rhesus C/E/D polypeptide

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0111562	overhydrated hereditary stomatocytosis	Alliance of Genome Resources
DOID:0050641	Rh deficiency syndrome	Alliance of Genome Resources
DOID:583	hemolytic anemia	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	19743	MGI:1202713
Rattus norvegicus	65207	RGD:61871

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements