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Ammonium transporter Rh type A

Summary

UniProt ID: Q02094
Gene Symbol: RH50 RHAG
Gene ID: 6005
Organism: Homo sapiens (human)

External Links

GlyGen: Q02094
PubChem: Q02094
The Human Metabolome Database: HMDBP01947
The O-GlcNAc Database: Q02094
O-GlcNAcAtlas: Q02094
Re-Glyco: Q02094

Annotation

Keyword: 3D-structure Alternative splicing Ammonia transport Direct protein sequencing Disease variant Glycoprotein Hereditary hemolytic anemia Proteomics identification Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
intracellular monoatomic ion homeostasis	IDA	PMID
carbon dioxide transport	IDA	PMID PMID PMID PMID
bicarbonate transport	TAS	Reactome Reactome
carbon dioxide transmembrane transport	IDA	PMID
erythrocyte development

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

transmembrane transport [inference]

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

cellular developmental process [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis

monoatomic cation homeostasis [inference]

multicellular organismal-level iron ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis

inorganic ion homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

gas transport [inference]

carbon dioxide transport

carbon dioxide transmembrane transport

organic cation transport [inference]

methylammonium transport [inference]

methylammonium transmembrane transport

organic anion transport [inference]

bicarbonate transport

one-carbon compound transport [inference]

carbon dioxide transport

carbon dioxide transmembrane transport

methylammonium transport [inference]

methylammonium transmembrane transport

transmembrane transport [inference]

nitrogen compound transport [inference]

amine transport [inference]

methylammonium transport [inference]

methylammonium transmembrane transport

ammonium transmembrane transport

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GO Term	Evidence Code	Reference
plasma membrane	TAS	PMID Reactome Reactome Reactome Reactome
plasma membrane	IDA	PMID PMID
plasma membrane	IEA	GO_REF
membrane	EXP	PMID PMID PMID
membrane	IDA	PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

ankyrin-1 complex

cellular anatomical structure [inference]

membrane

plasma membrane

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GO Term	Evidence Code	Reference
ammonium channel activity	TAS	Reactome Reactome
ammonium channel activity	IDA	PMID PMID PMID PMID PMID PMID PMID
ammonium channel activity	IGI	PMID
ammonium channel activity	IEA	GO_REF GO_REF
methylammonium transmembrane transporter activity	IDA	PMID

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

amine transmembrane transporter activity [inference]

methylammonium transmembrane transporter activity

passive transmembrane transporter activity [inference]

channel activity [inference]

ammonium channel activity

narrow pore channel activity [inference]

leak channel activity

carbon dioxide transmembrane transporter activity

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

ankyrin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRFTFPLMAIVLEIAMIVLFGLFVEYETDQTVLEQLNITKPTDMGIFFELYPLFQDVHVMIFVGFGFLMTFLKKYGFSSVGINLLVAALGLQWGTIVQGILQSQGQKFNIGIKNMINADFSAATVLISFGAVLGKTSPTQMLIMTILEIVFFAHNEYLVSEIFKASDIGASMTIHAFGAYFGLAVAGILYRSGLRKGHENEESAYYSDLFAMIGTLFLWMFWPSFNSAIAEPGDKQCRAIVNTYFSLAACVLTAFAFSSLVEHRGKLNMVHIQNATLAGGVAVGTCADMAIHPFGSMIIGSIAGMVSVLGYKFLTPLFTTKLRIHDTCGVHNLHGLPGVVGGLAGIVAVAMGASNTSMAMQAAALGSSIGTAVVGGLMTGLILKLPLWGQPSDQNCYDDSVYWKVPKTR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
37	N-linked (GlcNAc...) asparagine			UniProt GlyGen
355	N-linked (GlcNAc...) asparagine			UniProt GlyGen
371		29351928	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN)	Homo sapiens
Erythrocytes take up carbon dioxide and release oxygen	Homo sapiens
Erythrocytes take up oxygen and release carbon dioxide	Homo sapiens
Rhesus glycoproteins mediate ammonium transport	Homo sapiens

Disease

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0111562	overhydrated hereditary stomatocytosis	Alliance of Genome Resources
DOID:583	hemolytic anemia	Alliance of Genome Resources
DOID:0050641	Rh deficiency syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements