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MIRAGE
sodium voltage-gated channel beta subunit 2
Summary
- Gene Symbol
-
- SCN2B
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Atrial fibrillation
- Brugada syndrome
- Cell membrane
- Cell projection
- Disease variant
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Ion channel
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Signal
- Sodium transport
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemical synaptic transmission |
|
|
| nervous system development |
|
|
| response to heat |
|
|
| gene expression |
|
|
| positive regulation of sodium ion transport |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel complex |
|
|
| voltage-gated sodium channel complex |
|
|
| voltage-gated sodium channel complex |
|
|
| voltage-gated sodium channel complex |
|
|
| plasma membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel activity |
|
|
| protein binding |
|
|
| sodium channel regulator activity |
|
|
| sodium channel regulator activity |
|
|
| sodium channel regulator activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sodium channel subunit beta-2
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cardiac muscle cell action potential involved in contraction |
| membrane depolarization during cardiac muscle cell action potential |
| sodium channel regulator activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050650 | familial atrial fibrillation |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 72821 | MGI:106921 | |
| 25349 | RGD:3633 |
