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MIRAGE
ST3 beta-galactoside alpha-2,3-sialyltransferase 3

Summary
Gene Symbol
  • St3gal3
Organism
Rattus norvegicus (Norway rat)
NCBI Gene
64445
KEGG Gene ID
rno:64445
PubChem
64445
Alliance of Genome Resources
Annotation
Keyword
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Proteomics identification
  • Reference proteome
  • Secreted
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying all 4 entries
UniProt Protein Name
Q02734
  • Beta-galactoside alpha-2,3-sialyltransferase 3
  • Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase
  • N-acetyllactosaminide alpha-2,3-sialyltransferase
  • ST3Gal III
  • ST3N
  • Sialyltransferase 6
F1LM32
  • Beta-galactoside alpha-2,3-sialyltransferase 3
  • Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase
  • N-acetyllactosaminide alpha-2,3-sialyltransferase
  • ST3Gal III
  • ST3N
  • Sialyltransferase 6
A0A8I6GDQ1
  • Beta-galactoside alpha-2,3-sialyltransferase 3
  • Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase
  • N-acetyllactosaminide alpha-2,3-sialyltransferase
  • ST3Gal III
  • ST3N
  • Sialyltransferase 6
A6JZG3
  • Beta-galactoside alpha-2,3-sialyltransferase 3
  • Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase
  • N-acetyllactosaminide alpha-2,3-sialyltransferase
  • ST3Gal III
  • ST3N
  • Sialyltransferase 6
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 3 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
Sialyltransferase
KEGG BRITE Database
Orthology
K00781
Name
N-acetyllactosaminide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.3.6]
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R06153
Rhea

RHEA:52316

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + H+ + CMP
Enzyme
PMID

RHEA:18913

a neolactoside nLc4Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate
H+ + a neolactoside IV3-α-NeuAc-nLc4Cer(d18:1(4E)) + CMP
Enzyme
PMID
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP012703
Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026