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solute carrier family 7 member 1

Summary

Gene Symbol

SLC7A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

6541

KEGG Gene ID

PubChem

6541

Alliance of Genome Resources

HGNC:11057

Annotation

Keyword

Amino-acid transport
Cell membrane
Direct protein sequencing
Glycoprotein
Proteomics identification
Receptor
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P30825	Ecotropic retroviral leukemia receptor homolog Ecotropic retrovirus receptor homolog Solute carrier family 7 member 1 System Y+ basic amino acid transporter

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
amino acid transport	TAS
amino acid transport	IEA
L-amino acid transport	IDA
lysine transport	IDA
ornithine transport	IMP

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

import across plasma membrane [inference]

amino acid import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

symbiont entry into host [inference]

symbiont entry into host cell

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

ornithine transport

L-ornithine transmembrane transport

vascular transport [inference]

transport across blood-brain barrier

organic cation transport [inference]

ornithine transport

L-ornithine transmembrane transport

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

L-arginine import across plasma membrane

L-lysine transport [inference]

L-arginine transmembrane transport

organic anion transport [inference]

carboxylic acid transport [inference]

aromatic amino acid transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

L-amino acid transport

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

ornithine transport

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

aromatic amino acid transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

L-amino acid transport

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

ornithine transport

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

transmembrane transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

import across plasma membrane [inference]

amino acid import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

nitrogen compound transport [inference]

aromatic amino acid transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

L-amino acid transport

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

ornithine transport

L-ornithine transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

import into cell [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
L-ornithine transmembrane transporter activity	ISS
L-ornithine transmembrane transporter activity	IBA
L-ornithine transmembrane transporter activity	IEA
virus receptor activity	IEA
L-histidine transmembrane transporter activity	IDA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

azole transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

binding [inference]

protein binding

exogenous protein binding [inference]

virus receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	11987	MGI:88117
Saccharomyces cerevisiae S288C	854530	SGD:S000005875
Saccharomyces cerevisiae S288C	850665	SGD:S000003984
Saccharomyces cerevisiae S288C	855854	SGD:S000006195

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