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solute carrier family 18 member A2

Summary

Gene Symbol

SLC18A2

Organism

Homo sapiens (human)

External Links

NCBI Gene

6571

KEGG Gene ID

PubChem

6571

Alliance of Genome Resources

HGNC:10935

Annotation

Keyword

3D-structure
Alternative splicing
Cell projection
Cytoplasmic vesicle
Disease variant
Disulfide bond
Dystonia
Glycoprotein
Neurotransmitter transport
Parkinsonism
Phosphoprotein
Proteomics identification
Reference proteome
Synapse
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q05940	Solute carrier family 18 member 2 Vesicular amine transporter 2 Vesicular monoamine transporter 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
response to amphetamine
serotonin secretion by mast cell	IEA
histamine secretion by mast cell	IEA
neurotransmitter transport	TAS
neurotransmitter transport	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

intercellular transport [inference]

neurotransmitter loading into synaptic vesicle

aminergic neurotransmitter loading into synaptic vesicle

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

exocytic process [inference]

export from cell [inference]

secretion by cell [inference]

signal release [inference]

serotonin secretion [inference]

serotonin secretion involved in inflammatory response [inference]

serotonin secretion by mast cell

dopamine secretion [inference]

somato-dendritic dopamine secretion

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

catecholamine secretion [inference]

dopamine secretion [inference]

somato-dendritic dopamine secretion

multicellular organismal process [inference]

behavior [inference]

locomotory behavior

post-embryonic development

response to stimulus [inference]

response to chemical [inference]

response to toxic substance

response to nitrogen compound [inference]

response to amine [inference]

response to amphetamine

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

neurotransmitter transport

neurotransmitter uptake [inference]

histamine uptake

neurotransmitter reuptake [inference]

serotonin uptake

neurotransmitter loading into synaptic vesicle

aminergic neurotransmitter loading into synaptic vesicle

hormone transport [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

intercellular transport [inference]

neurotransmitter loading into synaptic vesicle

aminergic neurotransmitter loading into synaptic vesicle

organic hydroxy compound transport [inference]

serotonin transport

serotonin secretion [inference]

serotonin secretion involved in inflammatory response [inference]

serotonin secretion by mast cell

serotonin uptake

catecholamine transport [inference]

dopamine transport

dopamine secretion [inference]

somato-dendritic dopamine secretion

catecholamine secretion [inference]

dopamine secretion [inference]

somato-dendritic dopamine secretion

secretion [inference]

histamine secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

secretion by cell [inference]

signal release [inference]

serotonin secretion [inference]

serotonin secretion involved in inflammatory response [inference]

serotonin secretion by mast cell

dopamine secretion [inference]

somato-dendritic dopamine secretion

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

catecholamine secretion [inference]

dopamine secretion [inference]

somato-dendritic dopamine secretion

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

nitrogen compound transport [inference]

amine transport [inference]

aminergic neurotransmitter loading into synaptic vesicle

monoamine transport

serotonin transport

serotonin secretion [inference]

serotonin secretion involved in inflammatory response [inference]

serotonin secretion by mast cell

serotonin uptake

catecholamine transport [inference]

dopamine transport

dopamine secretion [inference]

somato-dendritic dopamine secretion

catecholamine secretion [inference]

dopamine secretion [inference]

somato-dendritic dopamine secretion

histamine transport [inference]

histamine secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

histamine uptake

import into cell [inference]

neurotransmitter uptake [inference]

histamine uptake

neurotransmitter reuptake [inference]

serotonin uptake

export from cell [inference]

secretion by cell [inference]

signal release [inference]

serotonin secretion [inference]

serotonin secretion involved in inflammatory response [inference]

serotonin secretion by mast cell

dopamine secretion [inference]

somato-dendritic dopamine secretion

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

catecholamine secretion [inference]

dopamine secretion [inference]

somato-dendritic dopamine secretion

establishment of localization in cell

neurotransmitter loading into synaptic vesicle

aminergic neurotransmitter loading into synaptic vesicle

neurotransmitter reuptake [inference]

serotonin uptake

somato-dendritic dopamine secretion

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of reactive oxygen species biosynthetic process

negative regulation of reactive oxygen species metabolic process [inference]

negative regulation of reactive oxygen species biosynthetic process

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of reactive oxygen species biosynthetic process

regulation of reactive oxygen species biosynthetic process [inference]

negative regulation of reactive oxygen species biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of reactive oxygen species biosynthetic process

negative regulation of reactive oxygen species metabolic process [inference]

negative regulation of reactive oxygen species biosynthetic process

regulation of reactive oxygen species metabolic process [inference]

regulation of reactive oxygen species biosynthetic process [inference]

negative regulation of reactive oxygen species biosynthetic process

negative regulation of reactive oxygen species metabolic process [inference]

negative regulation of reactive oxygen species biosynthetic process

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of reactive oxygen species biosynthetic process

negative regulation of reactive oxygen species metabolic process [inference]

negative regulation of reactive oxygen species biosynthetic process

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

Displaying entries **16 - 17** of 17 in total

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GO Term	Evidence Code	PMID
clathrin-sculpted monoamine transport vesicle membrane	IEA
dopaminergic synapse	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

microtubule organizing center [inference]

centrosome

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane

clathrin-sculpted monoamine transport vesicle membrane

exocytic vesicle membrane [inference]

synaptic vesicle membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-sculpted monoamine transport vesicle membrane

secretory granule membrane

bounding membrane of organelle [inference]

transport vesicle membrane

clathrin-sculpted monoamine transport vesicle membrane

exocytic vesicle membrane [inference]

synaptic vesicle membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-sculpted monoamine transport vesicle membrane

secretory granule membrane

cell junction [inference]

synapse [inference]

dopaminergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

presynapse [inference]

terminal bouton

Displaying **all 5** entries
GO Term	Evidence Code	PMID
serotonin:sodium:chloride symporter activity	IBA
protein binding	IPI
monoamine transmembrane transporter activity	TAS
monoamine:proton antiporter activity	IDA
transmembrane transporter activity	IEA